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Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients.
Koll CEM, Hopff SM, Meurers T, Lee CH, Kohls M, Stellbrink C, Thibeault C, Reinke L, Steinbrecher S, Schreiber S, Mitrov L, Frank S, Miljukov O, Erber J, Hellmuth JC, Reese JP, Steinbeis F, Bahmer T, Hagen M, Meybohm P, Hansch S, Vadász I, Krist L, Jiru-Hillmann S, Prasser F, Vehreschild JJ; NAPKON Study Group. Koll CEM, et al. Among authors: hellmuth jc. Sci Data. 2022 Dec 21;9(1):776. doi: 10.1038/s41597-022-01669-9. Sci Data. 2022. PMID: 36543828 Free PMC article.
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.
Duy C, Teater M, Garrett-Bakelman FE, Lee TC, Meydan C, Glass JL, Li M, Hellmuth JC, Mohammad HP, Smitheman KN, Shih AH, Abdel-Wahab O, Tallman MS, Guzman ML, Muench D, Grimes HL, Roboz GJ, Kruger RG, Creasy CL, Paietta EM, Levine RL, Carroll M, Melnick AM. Duy C, et al. Among authors: hellmuth jc. Cancer Discov. 2019 Jul;9(7):872-889. doi: 10.1158/2159-8290.CD-19-0106. Epub 2019 May 10. Cancer Discov. 2019. PMID: 31076479 Free PMC article.
Sequential therapy combining clofarabine and T-cell-replete HLA-haploidentical haematopoietic SCT is feasible and shows efficacy in the treatment of refractory or relapsed aggressive lymphoma.
Zoellner AK, Fritsch S, Prevalsek D, Engel N, Hubmann M, Reibke R, Rieger CT, Hellmuth JC, Haas M, Mumm F, Herold T, Ledderose G, Hiddemann W, Dreyling M, Hausmann A, Tischer J. Zoellner AK, et al. Among authors: hellmuth jc. Bone Marrow Transplant. 2015 May;50(5):679-84. doi: 10.1038/bmt.2014.328. Epub 2015 Feb 2. Bone Marrow Transplant. 2015. PMID: 25642765 Clinical Trial.
Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus.
Hoffmann FS, Schmidt A, Dittmann Chevillotte M, Wisskirchen C, Hellmuth J, Willms S, Gilmore RH, Glas J, Folwaczny M, Müller T, Berg T, Spengler U, Fitzmaurice K, Kelleher D, Reisch N, Rice CM, Endres S, Rothenfusser S. Hoffmann FS, et al. Hepatology. 2015 Feb;61(2):460-70. doi: 10.1002/hep.27344. Epub 2015 Jan 5. Hepatology. 2015. PMID: 25130193 Free PMC article.
Impact of age on genetics and treatment efficacy in follicular lymphoma.
Alig S, Jurinovic V, Pastore A, Bararia D, Häbe S, Hellmuth JC, Kridel R, Gascoyne R, Schmidt C, Zöllner AK, Buske C, Dreyling M, Unterhalt M, Hiddemann W, Hoster E, Weigert O. Alig S, et al. Among authors: hellmuth jc. Haematologica. 2018 Aug;103(8):e364-e367. doi: 10.3324/haematol.2018.187773. Epub 2018 Mar 15. Haematologica. 2018. PMID: 29545350 Free PMC article. No abstract available.
Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy.
Nicolai L, Leunig A, Brambs S, Kaiser R, Weinberger T, Weigand M, Muenchhoff M, Hellmuth JC, Ledderose S, Schulz H, Scherer C, Rudelius M, Zoller M, Höchter D, Keppler O, Teupser D, Zwißler B, von Bergwelt-Baildon M, Kääb S, Massberg S, Pekayvaz K, Stark K. Nicolai L, et al. Among authors: hellmuth jc. Circulation. 2020 Sep 22;142(12):1176-1189. doi: 10.1161/CIRCULATIONAHA.120.048488. Epub 2020 Jul 28. Circulation. 2020. PMID: 32755393 Free PMC article.
Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia.
Nicolai L, Leunig A, Brambs S, Kaiser R, Joppich M, Hoffknecht ML, Gold C, Engel A, Polewka V, Muenchhoff M, Hellmuth JC, Ruhle A, Ledderose S, Weinberger T, Schulz H, Scherer C, Rudelius M, Zoller M, Keppler OT, Zwißler B, von Bergwelt-Baildon M, Kääb S, Zimmer R, Bülow RD, von Stillfried S, Boor P, Massberg S, Pekayvaz K, Stark K. Nicolai L, et al. Among authors: hellmuth jc. J Thromb Haemost. 2021 Feb;19(2):574-581. doi: 10.1111/jth.15179. Epub 2020 Dec 20. J Thromb Haemost. 2021. PMID: 33217134 Free PMC article.
67 results