Denton JS - Search Results

1

Kir4.2 mediates proximal potassium effects on glutaminase activity and kidney injury.

Terker AS, Zhang Y, Arroyo JP, Cao S, Wang S, Fan X, Denton JS, Zhang MZ, Harris RC. Terker AS, et al. Among authors: denton js. Cell Rep. 2022 Dec 20;41(12):111840. doi: 10.1016/j.celrep.2022.111840. Cell Rep. 2022. PMID: 36543132 Free PMC article.

2

High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1.

Lewis LM, Bhave G, Chauder BA, Banerjee S, Lornsen KA, Redha R, Fallen K, Lindsley CW, Weaver CD, Denton JS. Lewis LM, et al. Among authors: denton js. Mol Pharmacol. 2009 Nov;76(5):1094-103. doi: 10.1124/mol.109.059840. Epub 2009 Aug 25. Mol Pharmacol. 2009. PMID: 19706730 Free PMC article.

3

Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel.

Bhave G, Chauder BA, Liu W, Dawson ES, Kadakia R, Nguyen TT, Lewis LM, Meiler J, Weaver CD, Satlin LM, Lindsley CW, Denton JS. Bhave G, et al. Among authors: denton js. Mol Pharmacol. 2011 Jan;79(1):42-50. doi: 10.1124/mol.110.066928. Epub 2010 Oct 6. Mol Pharmacol. 2011. PMID: 20926757 Free PMC article.

4

Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1.

Raphemot R, Kadakia RJ, Olsen ML, Banerjee S, Days E, Smith SS, Weaver CD, Denton JS. Raphemot R, et al. Among authors: denton js. Assay Drug Dev Technol. 2013 Nov-Dec;11(9-10):532-43. doi: 10.1089/adt.2013.544. Epub 2013 Nov 22. Assay Drug Dev Technol. 2013. PMID: 24266659 Free PMC article.

5

Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics.

Swale DR, Kharade SV, Denton JS. Swale DR, et al. Among authors: denton js. Curr Opin Pharmacol. 2014 Apr;15:7-15. doi: 10.1016/j.coph.2013.11.002. Epub 2013 Nov 26. Curr Opin Pharmacol. 2014. PMID: 24721648 Free PMC article. Review.

6

Next-generation inward rectifier potassium channel modulators: discovery and molecular pharmacology.

Weaver CD, Denton JS. Weaver CD, et al. Among authors: denton js. Am J Physiol Cell Physiol. 2021 Jun 1;320(6):C1125-C1140. doi: 10.1152/ajpcell.00548.2020. Epub 2021 Apr 7. Am J Physiol Cell Physiol. 2021. PMID: 33826405 Free PMC article. Review.

7

VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels.

McClenahan SJ, Kent CN, Kharade SV, Isaeva E, Williams JC, Han C, Terker A, Gresham R 3rd, Lazarenko RM, Days EL, Romaine IM, Bauer JA, Boutaud O, Sulikowski GA, Harris R, Weaver CD, Staruschenko A, Lindsley CW, Denton JS. McClenahan SJ, et al. Among authors: denton js. Mol Pharmacol. 2022 May;101(5):357-370. doi: 10.1124/molpharm.121.000464. Epub 2022 Mar 3. Mol Pharmacol. 2022. PMID: 35246480 Free PMC article.

8

Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2.

Zhang Y, Bock F, Ferdaus M, Arroyo JP, L Rose K, Patel P, Denton JS, Delpire E, Weinstein AM, Zhang MZ, Harris RC, Terker AS. Zhang Y, et al. Among authors: denton js. Nat Commun. 2024 Jun 17;15(1):5144. doi: 10.1038/s41467-024-49562-w. Nat Commun. 2024. PMID: 38886379 Free PMC article.

9

The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating.

Fallen K, Banerjee S, Sheehan J, Addison D, Lewis LM, Meiler J, Denton JS. Fallen K, et al. Among authors: denton js. Channels (Austin). 2009 Jan-Feb;3(1):57-68. doi: 10.4161/chan.3.1.7817. Epub 2009 Jan 6. Channels (Austin). 2009. PMID: 19221509 Free PMC article.

10

Small-molecule modulators of inward rectifier K+ channels: recent advances and future possibilities.

Bhave G, Lonergan D, Chauder BA, Denton JS. Bhave G, et al. Among authors: denton js. Future Med Chem. 2010 May;2(5):757-74. doi: 10.4155/fmc.10.179. Future Med Chem. 2010. PMID: 20543968 Free PMC article. Review.

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