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Page 1
Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease.
Friedrich VD, Pennitz P, Wyler E, Adler JM, Postmus D, Müller K, Teixeira Alves LG, Prigann J, Pott F, Vladimirova D, Hoefler T, Goekeri C, Landthaler M, Goffinet C, Saliba AE, Scholz M, Witzenrath M, Trimpert J, Kirsten H, Nouailles G. Friedrich VD, et al. Among authors: pennitz p. EBioMedicine. 2024 Oct;108:105312. doi: 10.1016/j.ebiom.2024.105312. Epub 2024 Sep 23. EBioMedicine. 2024. PMID: 39317638 Free article.
Single-cell-resolved interspecies comparison shows a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19.
Peidli S, Nouailles G, Wyler E, Adler JM, Kunder S, Voß A, Kazmierski J, Pott F, Pennitz P, Postmus D, Teixeira Alves LG, Goffinet C, Gruber AD, Blüthgen N, Witzenrath M, Trimpert J, Landthaler M, Praktiknjo SD. Peidli S, et al. Among authors: pennitz p. Cell Rep. 2024 Jun 25;43(6):114328. doi: 10.1016/j.celrep.2024.114328. Epub 2024 Jun 10. Cell Rep. 2024. PMID: 38861386 Free article.
Characterization of Commercially Available Human Primary Alveolar Epithelial Cells.
Herbst CJ, Lopez-Rodriguez E, Gluhovic V, Schulz S, Brandt R, Timm S, Abledu J, Falivene J, Pennitz P, Kirsten H, Nouailles G, Witzenrath M, Ochs M, Kuebler WM. Herbst CJ, et al. Among authors: pennitz p. Am J Respir Cell Mol Biol. 2024 May;70(5):339-350. doi: 10.1165/rcmb.2023-0320MA. Am J Respir Cell Mol Biol. 2024. PMID: 38207121
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.
Nouailles G, Adler JM, Pennitz P, Peidli S, Teixeira Alves LG, Baumgardt M, Bushe J, Voss A, Langenhagen A, Langner C, Martin Vidal R, Pott F, Kazmierski J, Ebenig A, Lange MV, Mühlebach MD, Goekeri C, Simmons S, Xing N, Abdelgawad A, Herwig S, Cichon G, Niemeyer D, Drosten C, Goffinet C, Landthaler M, Blüthgen N, Wu H, Witzenrath M, Gruber AD, Praktiknjo SD, Osterrieder N, Wyler E, Kunec D, Trimpert J. Nouailles G, et al. Among authors: pennitz p. Nat Microbiol. 2023 May;8(5):860-874. doi: 10.1038/s41564-023-01352-8. Epub 2023 Apr 3. Nat Microbiol. 2023. PMID: 37012419 Free PMC article.
MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia.
Goekeri C, Pennitz P, Groenewald W, Behrendt U, Kirsten H, Zobel CM, Berger S, Heinz GA, Mashreghi MF, Wienhold SM, Dietert K, Dorhoi A, Gruber AD, Scholz M, Rohde G, Suttorp N, Capnetz Study Group, Witzenrath M, Nouailles G. Goekeri C, et al. Among authors: pennitz p. Cells. 2023 Mar 21;12(6):959. doi: 10.3390/cells12060959. Cells. 2023. PMID: 36980300 Free PMC article.
A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics.
Pennitz P, Kirsten H, Friedrich VD, Wyler E, Goekeri C, Obermayer B, Heinz GA, Mashreghi MF, Büttner M, Trimpert J, Landthaler M, Suttorp N, Hocke AC, Hippenstiel S, Tönnies M, Scholz M, Kuebler WM, Witzenrath M, Hoenzke K, Nouailles G. Pennitz P, et al. Eur Respir Rev. 2022 Jul 27;31(165):220056. doi: 10.1183/16000617.0056-2022. Print 2022 Sep 30. Eur Respir Rev. 2022. PMID: 35896273 Free PMC article. Review.
Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics.
Wyler E, Adler JM, Eschke K, Teixeira Alves G, Peidli S, Pott F, Kazmierski J, Michalick L, Kershaw O, Bushe J, Andreotti S, Pennitz P, Abdelgawad A, Postmus D, Goffinet C, Kreye J, Reincke SM, Prüss H, Blüthgen N, Gruber AD, Kuebler WM, Witzenrath M, Landthaler M, Nouailles G, Trimpert J. Wyler E, et al. Among authors: pennitz p. Mol Ther. 2022 May 4;30(5):1952-1965. doi: 10.1016/j.ymthe.2022.03.014. Epub 2022 Mar 24. Mol Ther. 2022. PMID: 35339689 Free PMC article.
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Nouailles G, Wyler E, Pennitz P, Postmus D, Vladimirova D, Kazmierski J, Pott F, Dietert K, Muelleder M, Farztdinov V, Obermayer B, Wienhold SM, Andreotti S, Hoefler T, Sawitzki B, Drosten C, Sander LE, Suttorp N, Ralser M, Beule D, Gruber AD, Goffinet C, Landthaler M, Trimpert J, Witzenrath M. Nouailles G, et al. Among authors: pennitz p. Nat Commun. 2021 Aug 11;12(1):4869. doi: 10.1038/s41467-021-25030-7. Nat Commun. 2021. PMID: 34381043 Free PMC article.