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Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion.
Crozier TWM, Greenwood EJD, Williamson JC, Guo W, Porter LM, Gabaev I, Teixeira-Silva A, Grice GL, Wickenhagen A, Stanton RJ, Wang ECY, Wilson SJ, Matheson NJ, Nathan JA, McCaughan F, Lehner PJ. Crozier TWM, et al. Among authors: mccaughan f. Wellcome Open Res. 2022 Sep 7;7:224. doi: 10.12688/wellcomeopenres.17946.1. eCollection 2022. Wellcome Open Res. 2022. PMID: 36483314 Free PMC article.
SOX2 and squamous cancers.
Porter L, McCaughan F. Porter L, et al. Among authors: mccaughan f. Semin Cancer Biol. 2020 Dec;67(Pt 1):154-167. doi: 10.1016/j.semcancer.2020.05.007. Epub 2020 Sep 6. Semin Cancer Biol. 2020. PMID: 32905832 Review.
Cigarette smoke preferentially induces full length ACE2 expression in differentiated primary human airway cultures but does not alter the efficiency of cellular SARS-CoV-2 infection.
Porter LM, Guo W, Crozier TW, Greenwood EJ, Ortmann B, Kottmann D, Nathan JA, Mahadeva R, Lehner PJ, McCaughan F. Porter LM, et al. Among authors: mccaughan f. Heliyon. 2023 Mar;9(3):e14383. doi: 10.1016/j.heliyon.2023.e14383. Epub 2023 Mar 11. Heliyon. 2023. PMID: 36938474 Free PMC article.
In vitro platform to model the function of ionocytes in the human airway epithelium.
Vilà-González M, Pinte L, Fradique R, Causa E, Kool H, Rodrat M, Morell CM, Al-Thani M, Porter L, Guo W, Maeshima R, Hart SL, McCaughan F, Granata A, Sheppard DN, Floto RA, Rawlins EL, Cicuta P, Vallier L. Vilà-González M, et al. Among authors: mccaughan f. Respir Res. 2024 Apr 25;25(1):180. doi: 10.1186/s12931-024-02800-7. Respir Res. 2024. PMID: 38664797 Free PMC article.
Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters.
Neary M, Sharp J, Gallardo-Toledo E, Herriott J, Kijak E, Bramwell C, Cox H, Tatham L, Box H, Curley P, Arshad U, Rajoli RKR, Pertinez H, Valentijn A, Dhaliwal K, Mc Caughan F, Hobson J, Rannard S, Kipar A, Stewart JP, Owen A. Neary M, et al. Viruses. 2023 Aug 15;15(8):1744. doi: 10.3390/v15081744. Viruses. 2023. PMID: 37632086 Free PMC article.
Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies.
Han N, Hwang W, Tzelepis K, Schmerer P, Yankova E, MacMahon M, Lei W, M Katritsis N, Liu A, Felgenhauer U, Schuldt A, Harris R, Chapman K, McCaughan F, Weber F, Kouzarides T. Han N, et al. Among authors: mccaughan f. Sci Adv. 2021 Jun 30;7(27):eabh3032. doi: 10.1126/sciadv.abh3032. Print 2021 Jun. Sci Adv. 2021. PMID: 34193418 Free PMC article.
The SARS-CoV-2 viral load in COVID-19 patients is lower on face mask filters than on nasopharyngeal swabs.
Smolinska A, Jessop DS, Pappan KL, De Saedeleer A, Kang A, Martin AL, Allsworth M, Tyson C, Bos MP, Clancy M, Morel M, Cooke T, Dymond T, Harris C, Galloway J, Bresser P, Dijkstra N, Jagesar V, Savelkoul PHM, Beuken EVH, Nix WHV, Louis R, Delvaux M, Calmes D, Ernst B, Pollini S, Peired A, Guiot J, Tomassetti S, Budding AE, McCaughan F, Marciniak SJ, van der Schee MP. Smolinska A, et al. Among authors: mccaughan f. Sci Rep. 2021 Jun 29;11(1):13476. doi: 10.1038/s41598-021-92665-3. Sci Rep. 2021. PMID: 34188082 Free PMC article.
37 results