Loughney JW - Search Results

1

Overcoming Biopharmaceutical Interferents for Quantitation of Host Cell DNA Using an Automated, High-Throughput Methodology.

Lauro ML, Bowman AM, Smith JP, Gaye SN, Acevedo-Skrip J, DePhillips PA, Loughney JW. Lauro ML, et al. Among authors: loughney jw. AAPS J. 2022 Dec 8;25(1):10. doi: 10.1208/s12248-022-00764-4. AAPS J. 2022. PMID: 36482268 Free PMC article.

2

Soluble Human Cytomegalovirus gH/gL/pUL128-131 Pentameric Complex, but Not gH/gL, Inhibits Viral Entry to Epithelial Cells and Presents Dominant Native Neutralizing Epitopes.

Loughney JW, Rustandi RR, Wang D, Troutman MC, Dick LW Jr, Li G, Liu Z, Li F, Freed DC, Price CE, Hoang VM, Culp TD, DePhillips PA, Fu TM, Ha S. Loughney JW, et al. J Biol Chem. 2015 Jun 26;290(26):15985-95. doi: 10.1074/jbc.M115.652230. Epub 2015 May 6. J Biol Chem. 2015. PMID: 25947373 Free PMC article.

3

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex.

Ha S, Li F, Troutman MC, Freed DC, Tang A, Loughney JW, Wang D, Wang IM, Vlasak J, Nickle DC, Rustandi RR, Hamm M, DePhillips PA, Zhang N, McLellan JS, Zhu H, Adler SP, McVoy MA, An Z, Fu TM. Ha S, et al. Among authors: loughney jw. J Virol. 2017 Mar 13;91(7):e02033-16. doi: 10.1128/JVI.02033-16. Print 2017 Apr 1. J Virol. 2017. PMID: 28077654 Free PMC article.

4

Monoclonal Antibody Reagent Stability and Expiry Recommendation Combining Experimental Data with Mathematical Modeling.

Fink M, Cannon EM, Hofmann C, Patel N, Pauley C, Troutman M, Rustandi RR, Shank-Retzlaff M, Loughney J, Verch T. Fink M, et al. AAPS J. 2020 Nov 8;22(6):145. doi: 10.1208/s12248-020-00521-5. AAPS J. 2020. PMID: 33161491

5

Selective Plate-Based Assay for Trace EDTA Analysis via Boron Trifluoride-methanol Derivatization UHPLC-QqQ-MS/MS Enabling Biologic and Vaccine Processes.

Bennett R, Cohen RD, Wang H, Pereira T, Haverick MA, Loughney JW, Barbacci DC, Pristatsky P, Bowman AM, Losacco GL, Richardson DD, Mangion I, Regalado EL. Bennett R, et al. Among authors: loughney jw. Anal Chem. 2022 Jan 25;94(3):1678-1685. doi: 10.1021/acs.analchem.1c04224. Epub 2021 Dec 20. Anal Chem. 2022. PMID: 34928586

6

Greening automation: Wash and Re-use of disposable 384-well liquid handling tips to enable sustainable high-throughput vaccine development.

Pedrazzi B, Treyer A, Cohen R, Bowman A, Acevedo-Skrip J, Kearns K, Westover D, Loughney JW. Pedrazzi B, et al. Among authors: loughney jw. SLAS Technol. 2023 Oct;28(5):375-379. doi: 10.1016/j.slast.2023.06.003. Epub 2023 Jun 14. SLAS Technol. 2023. PMID: 37327946 Free article.

7

Development and Characterization of an In Vitro Cell-Based Assay to Predict Potency of mRNA-LNP-Based Vaccines.

Patel N, Davis Z, Hofmann C, Vlasak J, Loughney JW, DePhillips P, Mukherjee M. Patel N, et al. Among authors: loughney jw. Vaccines (Basel). 2023 Jul 10;11(7):1224. doi: 10.3390/vaccines11071224. Vaccines (Basel). 2023. PMID: 37515040 Free PMC article.

8

Residual bovine serum albumin (BSA) quantitation in vaccines using automated Capillary Western technology.

Loughney JW, Lancaster C, Ha S, Rustandi RR. Loughney JW, et al. Anal Biochem. 2014 Sep 15;461:49-56. doi: 10.1016/j.ab.2014.05.004. Epub 2014 May 17. Anal Biochem. 2014. PMID: 24841366

9

Development of a microchip capillary electrophoresis method for determination of the purity and integrity of mRNA in lipid nanoparticle vaccines.

Raffaele J, Loughney JW, Rustandi RR. Raffaele J, et al. Among authors: loughney jw. Electrophoresis. 2022 May;43(9-10):1101-1106. doi: 10.1002/elps.202100272. Epub 2021 Dec 19. Electrophoresis. 2022. PMID: 34806186 Free PMC article.

10

Quantitation of host cell proteins in biopharmaceuticals from chinese hamster ovarian and vero cell lines using capillary electrophoresis western blots.

Pearson C, Wang Y, Alkurdi E, Zhang Y, Yin K, Rustandi RR, Loughney JW. Pearson C, et al. Among authors: loughney jw. J Pharm Biomed Anal. 2023 Sep 5;233:115420. doi: 10.1016/j.jpba.2023.115420. Epub 2023 May 3. J Pharm Biomed Anal. 2023. PMID: 37207489 Review.

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