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Successful targeting of PD-1/PD-L1 with chimeric antigen receptor-natural killer cells and nivolumab in a humanized mouse cancer model.
Liu WN, So WY, Harden SL, Fong SY, Wong MXY, Tan WWS, Tan SY, Ong JKL, Rajarethinam R, Liu M, Cheng JY, Suteja L, Yeong JPS, Iyer NG, Lim DW, Chen Q. Liu WN, et al. Among authors: rajarethinam r. Sci Adv. 2022 Nov 25;8(47):eadd1187. doi: 10.1126/sciadv.add1187. Epub 2022 Nov 23. Sci Adv. 2022. PMID: 36417514 Free PMC article.
GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers.
Rasheed SAK, Leong HS, Lakshmanan M, Raju A, Dadlani D, Chong FT, Shannon NB, Rajarethinam R, Skanthakumar T, Tan EY, Hwang JSG, Lim KH, Tan DS, Ceppi P, Wang M, Tergaonkar V, Casey PJ, Iyer NG. Rasheed SAK, et al. Among authors: rajarethinam r. Oncogene. 2018 Mar;37(10):1340-1353. doi: 10.1038/s41388-017-0038-6. Epub 2017 Dec 19. Oncogene. 2018. PMID: 29255247 Free PMC article.
B7-H3-Targeting Chimeric Antigen Receptors Epstein-Barr Virus-specific T Cells Provides a Tumor Agnostic Off-The-Shelf Therapy Against B7-H3-positive Solid Tumors.
Yeo SP, Kua L, Tan JW, Lim JK, Wong FH, Santos MD, Poh CM, Goh AX, Koh XY, Zhou X, Rajarethinam R, Chen Q, Her Z, Horak ID, Low L, Tan KW. Yeo SP, et al. Among authors: rajarethinam r. Cancer Res Commun. 2024 Jun 4;4(6):1410-1429. doi: 10.1158/2767-9764.CRC-23-0538. Cancer Res Commun. 2024. PMID: 38717140 Free PMC article.
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.
Mzoughi S, Fong JY, Papadopoli D, Koh CM, Hulea L, Pigini P, Di Tullio F, Andreacchio G, Hoppe MM, Wollmann H, Low D, Caldez MJ, Peng Y, Torre D, Zhao JN, Uchenunu O, Varano G, Motofeanu CM, Lakshmanan M, Teo SX, Wun CM, Perini G, Tan SY, Ong CB, Al-Haddawi M, Rajarethinam R, Hue SS, Lim ST, Ong CK, Huang D, Ng SB, Bernstein E, Hasson D, Wee KB, Kaldis P, Jeyasekharan A, Dominguez-Sola D, Topisirovic I, Guccione E. Mzoughi S, et al. Among authors: rajarethinam r. Nat Commun. 2020 Jul 14;11(1):3520. doi: 10.1038/s41467-020-17064-0. Nat Commun. 2020. PMID: 32665551 Free PMC article.
A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection.
Gan ES, Syenina A, Linster M, Ng B, Zhang SL, Watanabe S, Rajarethinam R, Tan HC, Smith GJ, Ooi EE. Gan ES, et al. Among authors: rajarethinam r. Antiviral Res. 2021 Sep;193:105138. doi: 10.1016/j.antiviral.2021.105138. Epub 2021 Jul 8. Antiviral Res. 2021. PMID: 34246735 Free PMC article.
Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection.
Chan YH, Teo TH, Torres-Ruesta A, Hartimath SV, Chee RS, Khanapur S, Yong FF, Ramasamy B, Cheng P, Rajarethinam R, Robins EG, Goggi JL, Lum FM, Carissimo G, Rénia L, Ng LFP. Chan YH, et al. Among authors: rajarethinam r. Front Immunol. 2020 May 12;11:894. doi: 10.3389/fimmu.2020.00894. eCollection 2020. Front Immunol. 2020. PMID: 32477364 Free PMC article.
53 results