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Insights into distinct signaling profiles of the µOR activated by diverse agonists.
Qu Q, Huang W, Aydin D, Paggi JM, Seven AB, Wang H, Chakraborty S, Che T, DiBerto JF, Robertson MJ, Inoue A, Suomivuori CM, Roth BL, Majumdar S, Dror RO, Kobilka BK, Skiniotis G. Qu Q, et al. Among authors: wang h. Nat Chem Biol. 2023 Apr;19(4):423-430. doi: 10.1038/s41589-022-01208-y. Epub 2022 Nov 21. Nat Chem Biol. 2023. PMID: 36411392 Free PMC article.
New Malonate-Derived Tetraglucoside Detergents for Membrane Protein Stability.
Ehsan M, Katsube S, Cecchetti C, Du Y, Mortensen JS, Wang H, Nygaard A, Ghani L, Loland CJ, Kobilka BK, Byrne B, Guan L, Chae PS. Ehsan M, et al. Among authors: wang h. ACS Chem Biol. 2020 Jun 19;15(6):1697-1707. doi: 10.1021/acschembio.0c00316. Epub 2020 Jun 5. ACS Chem Biol. 2020. PMID: 32501004 Free PMC article.
Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study.
Das M, Mahler F, Hariharan P, Wang H, Du Y, Mortensen JS, Patallo EP, Ghani L, Glück D, Lee HJ, Byrne B, Loland CJ, Guan L, Kobilka BK, Keller S, Chae PS. Das M, et al. Among authors: wang h. J Am Chem Soc. 2020 Dec 23;142(51):21382-21392. doi: 10.1021/jacs.0c09629. Epub 2020 Dec 14. J Am Chem Soc. 2020. PMID: 33315387 Free PMC article.
Glyco-Steroidal Amphiphiles (GSAs) for Membrane Protein Structural Study.
Ehsan M, Wang H, Katsube S, Munk CF, Du Y, Youn T, Yoon S, Byrne B, Loland CJ, Guan L, Kobilka BK, Chae PS. Ehsan M, et al. Among authors: wang h. Chembiochem. 2022 Apr 5;23(7):e202200027. doi: 10.1002/cbic.202200027. Epub 2022 Feb 21. Chembiochem. 2022. PMID: 35129249 Free PMC article.
Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists.
Wang H, Hetzer F, Huang W, Qu Q, Meyerowitz J, Kaindl J, Hübner H, Skiniotis G, Kobilka BK, Gmeiner P. Wang H, et al. Angew Chem Int Ed Engl. 2022 Jun 27;61(26):e202200269. doi: 10.1002/anie.202200269. Epub 2022 Apr 29. Angew Chem Int Ed Engl. 2022. PMID: 35385593 Free PMC article.
Structure-based design of bitopic ligands for the µ-opioid receptor.
Faouzi A, Wang H, Zaidi SA, DiBerto JF, Che T, Qu Q, Robertson MJ, Madasu MK, El Daibani A, Varga BR, Zhang T, Ruiz C, Liu S, Xu J, Appourchaux K, Slocum ST, Eans SO, Cameron MD, Al-Hasani R, Pan YX, Roth BL, McLaughlin JP, Skiniotis G, Katritch V, Kobilka BK, Majumdar S. Faouzi A, et al. Among authors: wang h. Nature. 2023 Jan;613(7945):767-774. doi: 10.1038/s41586-022-05588-y. Epub 2022 Nov 30. Nature. 2023. PMID: 36450356 Free PMC article.
Negative allosteric modulation of the glucagon receptor by RAMP2.
Krishna Kumar K, O'Brien ES, Habrian CH, Latorraca NR, Wang H, Tuneew I, Montabana E, Marqusee S, Hilger D, Isacoff EY, Mathiesen JM, Kobilka BK. Krishna Kumar K, et al. Among authors: wang h. Cell. 2023 Mar 30;186(7):1465-1477.e18. doi: 10.1016/j.cell.2023.02.028. Cell. 2023. PMID: 37001505 Free PMC article.
150,898 results
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