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Page 1
Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss.
Hope DCD, Hinds CE, Lopes T, Vincent ML, Shrewsbury JV, Yu ATC, Davies I, Scott R, Jones B, Murphy KG, Minnion JS, Sardini A, Carling D, Lutz TA, Bloom SR, Tan TMM, Owen BM. Hope DCD, et al. Among authors: shrewsbury jv. Cell Rep Med. 2022 Nov 15;3(11):100810. doi: 10.1016/j.xcrm.2022.100810. Cell Rep Med. 2022. PMID: 36384093 Free PMC article.
Intra-islet glucagon signalling regulates beta-cell connectivity, first-phase insulin secretion and glucose homoeostasis.
Suba K, Patel Y, Martin-Alonso A, Hansen B, Xu X, Roberts A, Norton M, Chung P, Shrewsbury J, Kwok R, Kalogianni V, Chen S, Liu X, Kalyviotis K, Rutter GA, Jones B, Minnion J, Owen BM, Pantazis P, Distaso W, Drucker DJ, Tan TM, Bloom SR, Murphy KG, Salem V. Suba K, et al. Mol Metab. 2024 Jul;85:101947. doi: 10.1016/j.molmet.2024.101947. Epub 2024 Apr 26. Mol Metab. 2024. PMID: 38677509 Free PMC article.
Dietary protein defends lean mass and maintains the metabolic benefits of glucagon receptor agonism in mice.
Lopes T, Hope DC, Ramos-Pittol JM, Curtis A, Shrewsbury JV, Davies I, Zhou Z, Sardini A, Minnion JS, Dormann D, Bewick GA, Murphy KG, Carling D, Bloom SR, Tan TM, Owen BM. Lopes T, et al. Among authors: shrewsbury jv. Mol Metab. 2024 Nov;89:102024. doi: 10.1016/j.molmet.2024.102024. Epub 2024 Sep 3. Mol Metab. 2024. PMID: 39236784 Free PMC article.