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A Persistent Tuberculosis Outbreak in the UK Is Characterized by Hydrophobic fadB4-Deficient Mycobacterium tuberculosis That Replicates Rapidly in Macrophages.
Farzand R, Haigh RD, Monk P, Haldar P, Patel H, Pareek M, Verma R, Barer MR, Woltmann G, Ahyow L, Jagatia H, Decker J, Mukamolova GV, Cooper AM, Garton NJ, O'Hare HM. Farzand R, et al. Among authors: o hare hm. mBio. 2022 Dec 20;13(6):e0265622. doi: 10.1128/mbio.02656-22. Epub 2022 Nov 14. mBio. 2022. PMID: 36374090 Free PMC article.
Tuberculosis: feeding the enemy.
Garton NJ, O'Hare HM. Garton NJ, et al. Among authors: o hare hm. Chem Biol. 2013 Aug 22;20(8):971-2. doi: 10.1016/j.chembiol.2013.08.001. Chem Biol. 2013. PMID: 23973189
Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112.
Alqaseer K, Turapov O, Barthe P, Jagatia H, De Visch A, Roumestand C, Wegrzyn M, Bartek IL, Voskuil MI, O'Hare HM, Ajuh P, Bottrill AR, Witney AA, Cohen-Gonsaud M, Waddell SJ, Mukamolova GV. Alqaseer K, et al. Among authors: o hare hm. Mol Microbiol. 2019 Dec;112(6):1847-1862. doi: 10.1111/mmi.14398. Epub 2019 Oct 10. Mol Microbiol. 2019. PMID: 31562654 Free PMC article.
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis.
Rieck B, Degiacomi G, Zimmermann M, Cascioferro A, Boldrin F, Lazar-Adler NR, Bottrill AR, le Chevalier F, Frigui W, Bellinzoni M, Lisa MN, Alzari PM, Nguyen L, Brosch R, Sauer U, Manganelli R, O'Hare HM. Rieck B, et al. Among authors: o hare hm. PLoS Pathog. 2017 May 17;13(5):e1006399. doi: 10.1371/journal.ppat.1006399. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28545104 Free PMC article.
21 results