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Phage-assisted evolution and protein engineering yield compact, efficient prime editors.
Doman JL, Pandey S, Neugebauer ME, An M, Davis JR, Randolph PB, McElroy A, Gao XD, Raguram A, Richter MF, Everette KA, Banskota S, Tian K, Tao YA, Tolar J, Osborn MJ, Liu DR. Doman JL, et al. Among authors: tolar j. Cell. 2023 Aug 31;186(18):3983-4002.e26. doi: 10.1016/j.cell.2023.07.039. Cell. 2023. PMID: 37657419 Free PMC article.
Audacity of Gene Therapy.
Dimitrov M, Ebens CL, Tolar J. Dimitrov M, et al. Among authors: tolar j. Br J Dermatol. 2024 Aug 20:ljae332. doi: 10.1093/bjd/ljae332. Online ahead of print. Br J Dermatol. 2024. PMID: 39159995 No abstract available.
Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa-Associated Cutaneous Squamous Cell Carcinoma.
Lee CAA, Wu S, Chow YT, Kofman E, Williams V, Riddle M, Eide C, Ebens CL, Frank MH, Tolar J, Hook KP, AlDubayan SH, Frank NY. Lee CAA, et al. Among authors: tolar j. J Invest Dermatol. 2024 Jul;144(7):1534-1543.e2. doi: 10.1016/j.jid.2023.11.025. Epub 2024 Jan 23. J Invest Dermatol. 2024. PMID: 38272206 Free PMC article.
Allogeneic Hematopoietic Cell Transplant For Bone Marrow Failure or Myelodysplastic Syndrome in Dyskeratosis Congenita/Telomere Biology Disorders: Single-Center, Single-Arm, Open-Label Trial of Reduced-Intensity Conditioning Without Radiation.
Dimitrov M, Merkle S, Cao Q, Tryon RK, Vercellotti GM, Holtan SG, Kao RL, Srikanthan M, Terezakis SA, Tolar J, Ebens CL. Dimitrov M, et al. Among authors: tolar j. Transplant Cell Ther. 2024 Jul 11:S2666-6367(24)00530-X. doi: 10.1016/j.jtct.2024.07.007. Online ahead of print. Transplant Cell Ther. 2024. PMID: 39002862
Long-term survival after unrelated donor marrow transplantation for aplastic anaemia after optimized conditioning regimen: a retrospective multicentre cohort study.
Eapen M, Antin JH, Tolar J, Arai S, Horwitz ME, Kou J, Leifer E, McCarty JM, Nakamura R, Pulsipher MA, Rowley SD, Horowitz MM, Deeg HJ. Eapen M, et al. Among authors: tolar j. EClinicalMedicine. 2024 Sep 5;76:102819. doi: 10.1016/j.eclinm.2024.102819. eCollection 2024 Oct. EClinicalMedicine. 2024. PMID: 39290639 Free PMC article.
Chondroitin sulfate proteoglycan 4 (CSPG4) increases invasion of recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma by modifying TGFβ signaling.
Macaulay ARK, Yang J, Price MA, Forster CL, Riddle MJ, Ebens CL, Albert FW, Giubellino A, McCarthy JB, Tolar J. Macaulay ARK, et al. Among authors: tolar j. Br J Dermatol. 2024 Jul 17:ljae295. doi: 10.1093/bjd/ljae295. Online ahead of print. Br J Dermatol. 2024. PMID: 39018437
Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa.
Steinbeck BJ, Gao XD, McElroy AN, Pandey S, Doman JL, Riddle MJ, Xia L, Chen W, Eide CR, Lengert AH, Han SW, Blazar BR, Wandall HH, Dabelsteen S, Liu DR, Tolar J, Osborn MJ. Steinbeck BJ, et al. Among authors: tolar j. J Invest Dermatol. 2024 May 17:S0022-202X(24)00372-5. doi: 10.1016/j.jid.2024.04.013. Online ahead of print. J Invest Dermatol. 2024. PMID: 38763174
272 results