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TGFβ-specific T cells induced by a TGFβ-derived immune modulatory vaccine both directly and indirectly modulate the phenotype of tumor-associated macrophages and fibroblasts.
J Immunother Cancer. 2024 Feb 27;12(2):e008405. doi: 10.1136/jitc-2023-008405.
J Immunother Cancer. 2024.
PMID: 38417917
Free PMC article.
TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer.
Perez-Penco M, Weis-Banke SE, Schina A, Siersbæk M, Hübbe ML, Jørgensen MA, Lecoq I, Lara de la Torre L, Bendtsen SK, Martinenaite E, Holmström MO, Madsen DH, Donia M, Ødum N, Grøntved L, Andersen MH.
Perez-Penco M, et al.
J Immunother Cancer. 2022 Dec;10(12):e005491. doi: 10.1136/jitc-2022-005491.
J Immunother Cancer. 2022.
PMID: 36600556
Free PMC article.
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Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells.
Weis-Banke SE, Lisle TL, Perez-Penco M, Schina A, Hübbe ML, Siersbæk M, Holmström MO, Jørgensen MA, Marie Svane I, Met Ö, Ødum N, Madsen DH, Donia M, Grøntved L, Andersen MH.
Weis-Banke SE, et al. Among authors: perez penco m.
J Immunother Cancer. 2022 Oct;10(10):e005326. doi: 10.1136/jitc-2022-005326.
J Immunother Cancer. 2022.
PMID: 36316062
Free PMC article.
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CCL22-based peptide vaccines induce anti-cancer immunity by modulating tumor microenvironment.
Lecoq I, Kopp KL, Chapellier M, Mantas P, Martinenaite E, Perez-Penco M, Rønn Olsen L, Zocca MB, Wakatsuki Pedersen A, Andersen MH.
Lecoq I, et al. Among authors: perez penco m.
Oncoimmunology. 2022 Aug 29;11(1):2115655. doi: 10.1080/2162402X.2022.2115655. eCollection 2022.
Oncoimmunology. 2022.
PMID: 36052217
Free PMC article.
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Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment.
Bendtsen SK, Perez-Penco M, Hübbe ML, Martinenaite E, Orebo Holmström M, Weis-Banke SE, Grønne Dahlager Jørgensen N, Jørgensen MA, Munir Ahmad S, Jensen KM, Friese C, Lundsager MT, Johansen AZ, Carretta M, Ødum N, Met Ö, Svane IM, Madsen DH, Andersen MH.
Bendtsen SK, et al. Among authors: perez penco m.
Oncoimmunology. 2022 Jan 27;11(1):2026020. doi: 10.1080/2162402X.2022.2026020. eCollection 2022.
Oncoimmunology. 2022.
PMID: 35111385
Free PMC article.
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Arginase 1-Based Immune Modulatory Vaccines Induce Anticancer Immunity and Synergize with Anti-PD-1 Checkpoint Blockade.
Aaboe Jørgensen M, Ugel S, Linder Hübbe M, Carretta M, Perez-Penco M, Weis-Banke SE, Martinenaite E, Kopp K, Chapellier M, Adamo A, De Sanctis F, Frusteri C, Iezzi M, Zocca MB, Hargbøll Madsen D, Wakatsuki Pedersen A, Bronte V, Andersen MH.
Aaboe Jørgensen M, et al. Among authors: perez penco m.
Cancer Immunol Res. 2021 Nov;9(11):1316-1326. doi: 10.1158/2326-6066.CIR-21-0280. Epub 2021 Sep 13.
Cancer Immunol Res. 2021.
PMID: 34518197
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