Zheng M - Search Results

1

Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.

Hu CL, Chen BY, Li Z, Yang T, Xu CH, Yang R, Yu PC, Zhao J, Liu T, Liu N, Shan B, Zhang Q, Song J, Fei MY, Zong LJ, Zhang JY, Wu JC, Chen SB, Wang Y, Chang B, Hou D, Liu P, Jiang Y, Li X, Chen X, Deng CH, Ren YY, Wang R, Jin J, Xue K, Zhang Y, Du M, Shi J, Wu LY, Chang CK, Shen S, Chen Z, Chen SJ, Liu X, Sun XJ, Zheng M, Wang L. Hu CL, et al. Among authors: zheng m. Cell Res. 2022 Dec;32(12):1105-1123. doi: 10.1038/s41422-022-00735-6. Epub 2022 Oct 27. Cell Res. 2022. PMID: 36302855 Free PMC article.

2

Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening.

Guo W, Yao S, Sun P, Yang TB, Tang CP, Zheng MY, Ye Y, Meng LH. Guo W, et al. Acta Pharmacol Sin. 2020 Mar;41(3):423-431. doi: 10.1038/s41401-019-0246-4. Epub 2019 Jun 13. Acta Pharmacol Sin. 2020. PMID: 31197246 Free PMC article.

3

Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation.

Li X, Li Z, Wu X, Xiong Z, Yang T, Fu Z, Liu X, Tan X, Zhong F, Wan X, Wang D, Ding X, Yang R, Hou H, Li C, Liu H, Chen K, Jiang H, Zheng M. Li X, et al. Among authors: zheng m. J Med Chem. 2020 Aug 27;63(16):8723-8737. doi: 10.1021/acs.jmedchem.9b00855. Epub 2019 Aug 15. J Med Chem. 2020. PMID: 31364850

4

Discovery of novel glyceraldehyde-3-phosphate dehydrogenase inhibitor via docking-based virtual screening.

Li T, Tan X, Yang R, Miao Y, Zhang M, Xi Y, Guo R, Zheng M, Li B. Li T, et al. Among authors: zheng m. Bioorg Chem. 2020 Mar;96:103620. doi: 10.1016/j.bioorg.2020.103620. Epub 2020 Jan 25. Bioorg Chem. 2020. PMID: 32028064

5

TransformerCPI: improving compound-protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments.

Chen L, Tan X, Wang D, Zhong F, Liu X, Yang T, Luo X, Chen K, Jiang H, Zheng M. Chen L, et al. Among authors: zheng m. Bioinformatics. 2020 Aug 15;36(16):4406-4414. doi: 10.1093/bioinformatics/btaa524. Bioinformatics. 2020. PMID: 32428219

6

Discovery of triazoloquinoxaline as novel STING agonists via structure-based virtual screening.

Hou H, Yang R, Liu X, Wu X, Zhang S, Chen K, Zheng M. Hou H, et al. Among authors: zheng m. Bioorg Chem. 2020 Jul;100:103958. doi: 10.1016/j.bioorg.2020.103958. Epub 2020 May 20. Bioorg Chem. 2020. PMID: 32470762

7

Drug target inference by mining transcriptional data using a novel graph convolutional network framework.

Zhong F, Wu X, Yang R, Li X, Wang D, Fu Z, Liu X, Wan X, Yang T, Fan Z, Zhang Y, Luo X, Chen K, Zhang S, Jiang H, Zheng M. Zhong F, et al. Among authors: zheng m. Protein Cell. 2022 Apr;13(4):281-301. doi: 10.1007/s13238-021-00885-0. Epub 2021 Oct 22. Protein Cell. 2022. PMID: 34677780 Free PMC article.

8

Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation.

Tan X, Li C, Yang R, Zhao S, Li F, Li X, Chen L, Wan X, Liu X, Yang T, Tong X, Xu T, Cui R, Jiang H, Zhang S, Liu H, Zheng M. Tan X, et al. Among authors: zheng m. J Med Chem. 2022 Jan 13;65(1):103-119. doi: 10.1021/acs.jmedchem.1c01205. Epub 2021 Nov 25. J Med Chem. 2022. PMID: 34821145

9

Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer.

Chang J, Yang R, Chen L, Fan Z, Zhou J, Guo H, Zhang Y, Liu Y, Zhou G, Zhang K, Chen K, Jiang H, Zheng M, Zhang S. Chang J, et al. Among authors: zheng m. Acta Pharm Sin B. 2022 May;12(5):2619-2622. doi: 10.1016/j.apsb.2022.02.011. Epub 2022 Feb 16. Acta Pharm Sin B. 2022. PMID: 35646528 Free PMC article.

10

Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domain.

Zhou JY, Yang RR, Chang J, Song J, Fan ZS, Zhang YH, Lu CH, Jiang HL, Zheng MY, Zhang SL. Zhou JY, et al. Acta Pharmacol Sin. 2023 Feb;44(2):475-485. doi: 10.1038/s41401-022-00936-0. Epub 2022 Aug 2. Acta Pharmacol Sin. 2023. PMID: 35918411 Free PMC article.

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