Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Search Results
7 results
Filters applied: . Clear all
Results are displayed in a computed author sort order.
The Results By Year timeline is not available.
Page 1
Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA.
J Med Chem. 2022 Nov 10;65(21):14740-14763. doi: 10.1021/acs.jmedchem.2c01275. Epub 2022 Oct 21.
J Med Chem. 2022.
PMID: 36269107
Free PMC article.
Synthesis of novel 1,2-diarylpyrazolidin-3-one-based compounds and their evaluation as broad spectrum antibacterial agents.
Mokbel SA, Fathalla RK, El-Sharkawy LY, Abadi AH, Engel M, Abdel-Halim M.
Mokbel SA, et al. Among authors: fathalla rk.
Bioorg Chem. 2020 Jun;99:103759. doi: 10.1016/j.bioorg.2020.103759. Epub 2020 Mar 14.
Bioorg Chem. 2020.
PMID: 32220665
Item in Clipboard
From Celecoxib to a Novel Class of Phosphodiesterase 5 Inhibitors: Trisubstituted Pyrazolines as Novel Phosphodiesterase 5 Inhibitors with Extremely High Potency and Phosphodiesterase Isozyme Selectivity.
Abdel-Halim M, Sigler S, Racheed NAS, Hefnawy A, Fathalla RK, Hammam MA, Maher A, Maxuitenko Y, Keeton AB, Hartmann RW, Engel M, Piazza GA, Abadi AH.
Abdel-Halim M, et al. Among authors: fathalla rk.
J Med Chem. 2021 Apr 22;64(8):4462-4477. doi: 10.1021/acs.jmedchem.0c01120. Epub 2021 Apr 1.
J Med Chem. 2021.
PMID: 33793216
Item in Clipboard
Nanoparticle Fraught Liposomes: A Platform for Increased Antibiotic Selectivity in Multidrug Resistant Bacteria.
Fangary S, Abdel-Halim M, Fathalla RK, Hassan R, Farag N, Engel M, Mansour S, Tammam SN.
Fangary S, et al. Among authors: fathalla rk.
Mol Pharm. 2022 Sep 5;19(9):3163-3177. doi: 10.1021/acs.molpharmaceut.2c00258. Epub 2022 Jul 25.
Mol Pharm. 2022.
PMID: 35876358
Item in Clipboard
Targeting the binding pocket of the fluorophore 8-anilinonaphthalene-1-sulfonic acid in the bacterial enzyme MurA.
Fathalla RK, Engel M, Ducho C.
Fathalla RK, et al.
Arch Pharm (Weinheim). 2023 Sep;356(9):e2300237. doi: 10.1002/ardp.202300237. Epub 2023 Jul 18.
Arch Pharm (Weinheim). 2023.
PMID: 37464574
Item in Clipboard
Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity.
Wagdy RA, Abutaleb NS, Fathalla RK, Elgammal Y, Weck S, Pal R, Fischer PD, Ducho C, Abadi AH, N Seleem M, Engel M, Abdel-Halim M.
Wagdy RA, et al. Among authors: fathalla rk.
Eur J Med Chem. 2023 Dec 5;261:115789. doi: 10.1016/j.ejmech.2023.115789. Epub 2023 Sep 4.
Eur J Med Chem. 2023.
PMID: 37717380
Item in Clipboard
Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription.
Sigler S, Abdel-Halim M, Fathalla RK, Da Silva LM, Keeton AB, Maxuitenko YY, Berry K, Zhou G, Engel M, Abadi AH, Piazza GA.
Sigler S, et al. Among authors: fathalla rk.
Anticancer Agents Med Chem. 2024 Sep 2. doi: 10.2174/0118715206318802240821114353. Online ahead of print.
Anticancer Agents Med Chem. 2024.
PMID: 39225209
Item in Clipboard
Cite
Cite