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Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection.
VanDyke D, Iglesias M, Tomala J, Young A, Smith J, Perry JA, Gebara E, Cross AR, Cheung LS, Dykema AG, Orcutt-Jahns BT, Henclová T, Golias J, Balolong J, Tomasovic LM, Funda D, Meyer AS, Pardoll DM, Hester J, Issa F, Hunter CA, Anderson MS, Bluestone JA, Raimondi G, Spangler JB. VanDyke D, et al. Among authors: funda d. Cell Rep. 2022 Oct 18;41(3):111478. doi: 10.1016/j.celrep.2022.111478. Cell Rep. 2022. PMID: 36261022 Free PMC article.
Antigen Loading (e.g., Glutamic Acid Decarboxylase 65) of Tolerogenic DCs (tolDCs) Reduces Their Capacity to Prevent Diabetes in the Non-Obese Diabetes (NOD)-Severe Combined Immunodeficiency Model of Adoptive Cotransfer of Diabetes As Well As in NOD Mice.
Funda DP, Goliáš J, Hudcovic T, Kozáková H, Špíšek R, Palová-Jelínková L. Funda DP, et al. Front Immunol. 2018 Feb 16;9:290. doi: 10.3389/fimmu.2018.00290. eCollection 2018. Front Immunol. 2018. PMID: 29503651 Free PMC article.
Autoimmunity, immunodeficiency and mucosal infections: chronic intestinal inflammation as a sensitive indicator of immunoregulatory defects in response to normal luminal microflora.
Tlaskalová-Hogenová H, Stĕpánková R, Tucková L, Farré MA, Funda DP, Verdú EF, Sinkora J, Hudcovic T, Reháková Z, Cukrowska B, Kozáková H, Prokesová L. Tlaskalová-Hogenová H, et al. Among authors: funda dp. Folia Microbiol (Praha). 1998;43(5):545-50. doi: 10.1007/BF02820817. Folia Microbiol (Praha). 1998. PMID: 9821323 Review.
Protective Effect of Vegan Microbiota on Liver Steatosis Is Conveyed by Dietary Fiber: Implications for Fecal Microbiota Transfer Therapy.
Daskova N, Heczkova M, Modos I, Hradecky J, Hudcovic T, Kuzma M, Pelantova H, Buskova I, Sticova E, Funda D, Golias J, Drabonova B, Jarkovska J, Kralova M, Cibulkova I, Gojda J, Cahova M. Daskova N, et al. Among authors: funda d. Nutrients. 2023 Jan 15;15(2):454. doi: 10.3390/nu15020454. Nutrients. 2023. PMID: 36678325 Free PMC article.
The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases.
Tlaskalová-Hogenová H, Stěpánková R, Kozáková H, Hudcovic T, Vannucci L, Tučková L, Rossmann P, Hrnčíř T, Kverka M, Zákostelská Z, Klimešová K, Přibylová J, Bártová J, Sanchez D, Fundová P, Borovská D, Srůtková D, Zídek Z, Schwarzer M, Drastich P, Funda DP. Tlaskalová-Hogenová H, et al. Among authors: funda dp. Cell Mol Immunol. 2011 Mar;8(2):110-20. doi: 10.1038/cmi.2010.67. Epub 2011 Jan 31. Cell Mol Immunol. 2011. PMID: 21278760 Free PMC article. Review.
Tolerogenic Dendritic Cells from Poorly Compensated Type 1 Diabetes Patients Have Decreased Ability To Induce Stable Antigen-Specific T Cell Hyporesponsiveness and Generation of Suppressive Regulatory T Cells.
Dáňová K, Grohová A, Strnadová P, Funda DP, Šumník Z, Lebl J, Cinek O, Průhová Š, Koloušková S, Obermannová B, Petruželková L, Šedivá A, Fundová P, Buschard K, Špíšek R, Palová-Jelínková L. Dáňová K, et al. J Immunol. 2017 Jan 15;198(2):729-740. doi: 10.4049/jimmunol.1600676. Epub 2016 Dec 7. J Immunol. 2017. PMID: 27927966
Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases.
Tlaskalová-Hogenová H, Stepánková R, Hudcovic T, Tucková L, Cukrowska B, Lodinová-Zádníková R, Kozáková H, Rossmann P, Bártová J, Sokol D, Funda DP, Borovská D, Reháková Z, Sinkora J, Hofman J, Drastich P, Kokesová A. Tlaskalová-Hogenová H, et al. Among authors: funda dp. Immunol Lett. 2004 May 15;93(2-3):97-108. doi: 10.1016/j.imlet.2004.02.005. Immunol Lett. 2004. PMID: 15158604 Review.
46 results