Weir ANM - Search Results

1

Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin.

Winter AJ, Rowe MT, Weir ANM, Akter N, Mbatha SZ, Walker PD, Williams C, Song Z, Race PR, Willis CL, Crump MP. Winter AJ, et al. Among authors: weir anm. Angew Chem Int Ed Engl. 2022 Dec 12;61(50):e202212393. doi: 10.1002/anie.202212393. Epub 2022 Nov 10. Angew Chem Int Ed Engl. 2022. PMID: 36227272 Free PMC article.

2

Control of β-Branching in Kalimantacin Biosynthesis: Application of ¹³ C NMR to Polyketide Programming.

Walker PD, Williams C, Weir ANM, Wang L, Crosby J, Race PR, Simpson TJ, Willis CL, Crump MP. Walker PD, et al. Among authors: weir anm. Angew Chem Int Ed Engl. 2019 Sep 2;58(36):12446-12450. doi: 10.1002/anie.201905482. Epub 2019 Aug 7. Angew Chem Int Ed Engl. 2019. PMID: 31294525

3

A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis.

Walker PD, Rowe MT, Winter AJ, Weir ANM, Akter N, Wang L, Race PR, Williams C, Song Z, Simpson TJ, Willis CL, Crump MP. Walker PD, et al. Among authors: weir anm. ACS Chem Biol. 2020 Feb 21;15(2):494-503. doi: 10.1021/acschembio.9b00969. Epub 2020 Feb 6. ACS Chem Biol. 2020. PMID: 31977176

4

The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI.

Fage CD, Lathouwers T, Vanmeert M, Gao LJ, Vrancken K, Lammens EM, Weir ANM, Degroote R, Cuppens H, Kosol S, Simpson TJ, Crump MP, Willis CL, Herdewijn P, Lescrinier E, Lavigne R, Anné J, Masschelein J. Fage CD, et al. Among authors: weir anm. Angew Chem Int Ed Engl. 2020 Jun 22;59(26):10549-10556. doi: 10.1002/anie.201915407. Epub 2020 Apr 14. Angew Chem Int Ed Engl. 2020. PMID: 32208550

5

Total Synthesis of Kalimantacin A.

Davies JA, Bull FM, Walker PD, Weir ANM, Lavigne R, Masschelein J, Simpson TJ, Race PR, Crump MP, Willis CL. Davies JA, et al. Among authors: weir anm. Org Lett. 2020 Aug 21;22(16):6349-6353. doi: 10.1021/acs.orglett.0c02190. Epub 2020 Aug 10. Org Lett. 2020. PMID: 32806153

6

Polyketide β-branching: diversity, mechanism and selectivity.

Walker PD, Weir ANM, Willis CL, Crump MP. Walker PD, et al. Among authors: weir anm. Nat Prod Rep. 2021 Apr 28;38(4):723-756. doi: 10.1039/d0np00045k. Nat Prod Rep. 2021. PMID: 33057534 Review.

7

Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer Agents.

Vriens E, De Ruysscher D, Weir ANM, Dekimpe S, Steurs G, Shemy A, Persoons L, Santos AR, Williams C, Daelemans D, Crump MP, Voet A, De Borggraeve W, Lescrinier E, Masschelein J. Vriens E, et al. Among authors: weir anm. Angew Chem Int Ed Engl. 2023 Aug 21;62(34):e202304476. doi: 10.1002/anie.202304476. Epub 2023 Jun 30. Angew Chem Int Ed Engl. 2023. PMID: 37218580

8

Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin.

Winter AJ, Rowe MT, Weir ANM, Akter N, Mbatha SZ, Walker PD, Williams C, Song Z, Race PR, Willis CL, Crump MP. Winter AJ, et al. Among authors: weir anm. Angew Chem Weinheim Bergstr Ger. 2022 Dec 12;134(50):e202212393. doi: 10.1002/ange.202212393. Epub 2022 Nov 10. Angew Chem Weinheim Bergstr Ger. 2022. PMID: 38505625 Free PMC article.

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