You WK - Search Results

1

Targeting the DLL/Notch Signaling Pathway in Cancer: Challenges and Advances in Clinical Development.

You WK, Schuetz TJ, Lee SH. You WK, et al. Mol Cancer Ther. 2023 Jan 3;22(1):3-11. doi: 10.1158/1535-7163.MCT-22-0243. Mol Cancer Ther. 2023. PMID: 36223541 Free PMC article. Review.

2

Simultaneous blockade of VEGF and Dll4 by HD105, a bispecific antibody, inhibits tumor progression and angiogenesis.

Lee D, Kim D, Choi YB, Kang K, Sung ES, Ahn JH, Goo J, Yeom DH, Jang HS, Moon KD, Lee SH, You WK. Lee D, et al. Among authors: you wk. MAbs. 2016 Jul;8(5):892-904. doi: 10.1080/19420862.2016.1171432. Epub 2016 Apr 6. MAbs. 2016. PMID: 27049350 Free PMC article.

3

Development, validation, and application of ELISA for detection of anti-HD105 antibodies in pre-clinical safety evaluation using monkeys.

Choi WH, Jo HR, Jeon EJ, Youm SY, Jeon JS, Son YG, You WK, Koh WS, Lee SH, Kim SK. Choi WH, et al. Among authors: you wk. J Pharm Biomed Anal. 2016 Nov 30;131:309-315. doi: 10.1016/j.jpba.2016.09.009. Epub 2016 Sep 5. J Pharm Biomed Anal. 2016. PMID: 27619177

4

High delta-like ligand 4 expression correlates with a poor clinical outcome in gastric cancer.

Kim Y, Byeon SJ, Hur J, Lee K, Kim D, Ahn JH, Lee SH, You WK, Kim ST, Park SH, Kang WK, Kim KM, Lee J. Kim Y, et al. Among authors: you wk. J Cancer. 2019 Jun 2;10(14):3172-3178. doi: 10.7150/jca.30257. eCollection 2019. J Cancer. 2019. PMID: 31289587 Free PMC article.

5

Synergistic antitumor activity of a DLL4/VEGF bispecific therapeutic antibody in combination with irinotecan in gastric cancer.

Kim DH, Lee S, Kang HG, Park HW, Lee HW, Kim D, Yoem DH, Ahn JH, Ha E, You WK, Lee SH, Kim SJ, Chun KH. Kim DH, et al. Among authors: you wk. BMB Rep. 2020 Nov;53(10):533-538. doi: 10.5483/BMBRep.2020.53.10.103. BMB Rep. 2020. PMID: 32580836 Free PMC article.

6

ABL001, a Bispecific Antibody Targeting VEGF and DLL4, with Chemotherapy, Synergistically Inhibits Tumor Progression in Xenograft Models.

Yeom DH, Lee YS, Ryu I, Lee S, Sung B, Lee HB, Kim D, Ahn JH, Ha E, Choi YS, Lee SH, You WK. Yeom DH, et al. Among authors: you wk. Int J Mol Sci. 2020 Dec 29;22(1):241. doi: 10.3390/ijms22010241. Int J Mol Sci. 2020. PMID: 33383646 Free PMC article.

7

N-terminal selective conjugation method widens the therapeutic window of antibody-drug conjugates by improving tolerability and stability.

Ko MJ, Song D, Kim J, Kim JY, Eom J, Sung B, Son YG, Kim YM, Lee SH, You WK, Jung J. Ko MJ, et al. Among authors: you wk. MAbs. 2021 Jan-Dec;13(1):1914885. doi: 10.1080/19420862.2021.1914885. MAbs. 2021. PMID: 33904380 Free PMC article.

8

Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier.

Shin JW, An S, Kim D, Kim H, Ahn J, Eom J, You WK, Yun H, Lee B, Sung B, Jung J, Kim S, Son Y, Sung E, Lee H, Lee S, Song D, Pak Y, Sandhu JK, Haqqani AS, Stanimirovic DB, Yoo J, Kim D, Maeng S, Lee J, Lee SH. Shin JW, et al. Among authors: you wk. Cell Rep Methods. 2022 Nov 21;2(11):100338. doi: 10.1016/j.crmeth.2022.100338. eCollection 2022 Nov 21. Cell Rep Methods. 2022. PMID: 36452865 Free PMC article.

9

Population pharmacokinetic model of ABL001/CTX-009 (anti-VEGF/DLL4) in adult cancer patients with solid tumor.

Na JY, Jeon J, Huh KY, Yu KS, Lee S, Eom J, Ahn J, You WK, Oh J. Na JY, et al. Among authors: you wk. Cancer Sci. 2024 Dec;115(12):3943-3951. doi: 10.1111/cas.16363. Epub 2024 Oct 7. Cancer Sci. 2024. PMID: 39375952 Free PMC article. Clinical Trial.

10

Development of antibody-based c-Met inhibitors for targeted cancer therapy.

Lee D, Sung ES, Ahn JH, An S, Huh J, You WK. Lee D, et al. Among authors: you wk. Immunotargets Ther. 2015 Feb 9;4:35-44. doi: 10.2147/ITT.S37409. eCollection 2015. Immunotargets Ther. 2015. PMID: 27471710 Free PMC article. Review.

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