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The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype.
Barut GT, Halwe NJ, Taddeo A, Kelly JN, Schön J, Ebert N, Ulrich L, Devisme C, Steiner S, Trüeb BS, Hoffmann B, Veiga IB, Leborgne NGF, Moreira EA, Breithaupt A, Wylezich C, Höper D, Wernike K, Godel A, Thomann L, Flück V, Stalder H, Brügger M, Esteves BIO, Zumkehr B, Beilleau G, Kratzel A, Schmied K, Ochsenbein S, Lang RM, Wider M, Machahua C, Dorn P, Marti TM, Funke-Chambour M, Rauch A, Widera M, Ciesek S, Dijkman R, Hoffmann D, Alves MP, Benarafa C, Beer M, Thiel V. Barut GT, et al. Among authors: benarafa c. Nat Commun. 2022 Oct 7;13(1):5929. doi: 10.1038/s41467-022-33632-y. Nat Commun. 2022. PMID: 36207334 Free PMC article.
SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Kelly JN, Fan X, Hoffmann B, Steiner S, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson M, Keller M, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: benarafa c. bioRxiv [Preprint]. 2020 Oct 27:2020.10.27.357558. doi: 10.1101/2020.10.27.357558. bioRxiv. 2020. Update in: Nature. 2021 Apr;592(7852):122-127. doi: 10.1038/s41586-021-03361-1. PMID: 33140052 Free PMC article. Updated. Preprint.
SARS-CoV-2 spike D614G change enhances replication and transmission.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Steiner S, Kelly JN, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Fan X, Hoffmann B, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson MM, Keller MW, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: benarafa c. Nature. 2021 Apr;592(7852):122-127. doi: 10.1038/s41586-021-03361-1. Epub 2021 Feb 26. Nature. 2021. PMID: 33636719
The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis.
Démoulins T, Brügger M, Zumkehr B, Oliveira Esteves BI, Mehinagic K, Fahmi A, Borcard L, Taddeo A, Jandrasits D, Posthaus H, Benarafa C, Ruggli N, Alves MP. Démoulins T, et al. Among authors: benarafa c. PLoS Pathog. 2021 Apr 28;17(4):e1009529. doi: 10.1371/journal.ppat.1009529. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33909707 Free PMC article.
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta.
Ulrich L, Halwe NJ, Taddeo A, Ebert N, Schön J, Devisme C, Trüeb BS, Hoffmann B, Wider M, Fan X, Bekliz M, Essaidi-Laziosi M, Schmidt ML, Niemeyer D, Corman VM, Kraft A, Godel A, Laloli L, Kelly JN, Calderon BM, Breithaupt A, Wylezich C, Berenguer Veiga I, Gultom M, Osman S, Zhou B, Adea K, Meyer B, Eberhardt CS, Thomann L, Gsell M, Labroussaa F, Jores J, Summerfield A, Drosten C, Eckerle IA, Wentworth DE, Dijkman R, Hoffmann D, Thiel V, Beer M, Benarafa C. Ulrich L, et al. Among authors: benarafa c. Nature. 2022 Feb;602(7896):307-313. doi: 10.1038/s41586-021-04342-0. Epub 2021 Dec 22. Nature. 2022. PMID: 34937050 Free PMC article.
60 results