Zheng N - Search Results

1

Loss-of-function variants in MYCBP2 cause neurobehavioural phenotypes and corpus callosum defects.

AlAbdi L, Desbois M, Rusnac DV, Sulaiman RA, Rosenfeld JA, Lalani S, Murdock DR, Burrage LC; Undiagnosed Diseases Network; Billie Au PY, Towner S, Wilson WG, Wong L, Brunet T, Strobl-Wildemann G, Burton JE, Hoganson G, McWalter K, Begtrup A, Zarate YA, Christensen EL, Opperman KJ, Giles AC, Helaby R, Kania A, Zheng N, Grill B, Alkuraya FS. AlAbdi L, et al. Among authors: zheng n. Brain. 2023 Apr 19;146(4):1373-1387. doi: 10.1093/brain/awac364. Brain. 2023. PMID: 36200388 Free PMC article.

2

C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases.

Lin HC, Yeh CW, Chen YF, Lee TT, Hsieh PY, Rusnac DV, Lin SY, Elledge SJ, Zheng N, Yen HS. Lin HC, et al. Among authors: zheng n. Mol Cell. 2018 May 17;70(4):602-613.e3. doi: 10.1016/j.molcel.2018.04.006. Mol Cell. 2018. PMID: 29775578 Free PMC article.

3

An artificial intelligence accelerated virtual screening platform for drug discovery.

Zhou G, Rusnac DV, Park H, Canzani D, Nguyen HM, Stewart L, Bush MF, Nguyen PT, Wulff H, Yarov-Yarovoy V, Zheng N, DiMaio F. Zhou G, et al. Among authors: zheng n. Nat Commun. 2024 Sep 5;15(1):7761. doi: 10.1038/s41467-024-52061-7. Nat Commun. 2024. PMID: 39237523 Free PMC article.

4

Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.

Wang H, Curran EC, Hinds TR, Wang EH, Zheng N. Wang H, et al. Among authors: zheng n. Cell Res. 2014 Dec;24(12):1433-44. doi: 10.1038/cr.2014.148. Epub 2014 Nov 21. Cell Res. 2014. PMID: 25412659 Free PMC article.

5

Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.

Wisedchaisri G, Gamal El-Din TM, Powell NM, Zheng N, Catterall WA. Wisedchaisri G, et al. Among authors: zheng n. J Gen Physiol. 2023 Dec 4;155(12):e202313450. doi: 10.1085/jgp.202313450. Epub 2023 Oct 30. J Gen Physiol. 2023. PMID: 37903281 Free PMC article.

6

A ubiquitin-like protein unleashes ubiquitin ligases.

Saifee NH, Zheng N. Saifee NH, et al. Among authors: zheng n. Cell. 2008 Oct 17;135(2):209-11. doi: 10.1016/j.cell.2008.09.049. Cell. 2008. PMID: 18957195 Free article.

7

Repression by the Arabidopsis TOPLESS corepressor requires association with the core mediator complex.

Leydon AR, Wang W, Gala HP, Gilmour S, Juarez-Solis S, Zahler ML, Zemke JE, Zheng N, Nemhauser JL. Leydon AR, et al. Among authors: zheng n. Elife. 2021 Jun 2;10:e66739. doi: 10.7554/eLife.66739. Elife. 2021. PMID: 34075876 Free PMC article.

8

The conformational cycle of a prototypical voltage-gated sodium channel.

Catterall WA, Wisedchaisri G, Zheng N. Catterall WA, et al. Among authors: zheng n. Nat Chem Biol. 2020 Dec;16(12):1314-1320. doi: 10.1038/s41589-020-0644-4. Epub 2020 Nov 16. Nat Chem Biol. 2020. PMID: 33199904 Free PMC article. Review.

9

Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.

Welcker M, Wang B, Rusnac DV, Hussaini Y, Swanger J, Zheng N, Clurman BE. Welcker M, et al. Among authors: zheng n. Sci Adv. 2022 Jan 28;8(4):eabl7872. doi: 10.1126/sciadv.abl7872. Epub 2022 Jan 28. Sci Adv. 2022. PMID: 35089787 Free PMC article.

10

Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na_V1.7.

Wisedchaisri G, Gamal El-Din TM, Zheng N, Catterall WA. Wisedchaisri G, et al. Among authors: zheng n. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2219624120. doi: 10.1073/pnas.2219624120. Epub 2023 Mar 30. Proc Natl Acad Sci U S A. 2023. PMID: 36996107 Free PMC article.

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