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Adipose tissue retains an epigenetic memory of obesity after weight loss.
Hinte LC, Castellano-Castillo D, Ghosh A, Melrose K, Gasser E, Noé F, Massier L, Dong H, Sun W, Hoffmann A, Wolfrum C, Rydén M, Mejhert N, Blüher M, von Meyenn F. Hinte LC, et al. Among authors: melrose k. Nature. 2024 Nov 18. doi: 10.1038/s41586-024-08165-7. Online ahead of print. Nature. 2024. PMID: 39558077
H3K18 lactylation marks tissue-specific active enhancers.
Galle E, Wong CW, Ghosh A, Desgeorges T, Melrose K, Hinte LC, Castellano-Castillo D, Engl M, de Sousa JA, Ruiz-Ojeda FJ, De Bock K, Ruiz JR, von Meyenn F. Galle E, et al. Among authors: melrose k. Genome Biol. 2022 Oct 3;23(1):207. doi: 10.1186/s13059-022-02775-y. Genome Biol. 2022. PMID: 36192798 Free PMC article.