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Page 1
Heterozygous variants of CLPB are a cause of severe congenital neutropenia.
Warren JT, Cupo RR, Wattanasirakul P, Spencer DH, Locke AE, Makaryan V, Bolyard AA, Kelley ML, Kingston NL, Shorter J, Bellanné-Chantelot C, Donadieu J, Dale DC, Link DC. Warren JT, et al. Among authors: cupo rr. Blood. 2022 Feb 3;139(5):779-791. doi: 10.1182/blood.2021010762. Blood. 2022. PMID: 34115842 Free PMC article.
Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity.
Eisner V, Cupo RR, Gao E, Csordás G, Slovinsky WS, Paillard M, Cheng L, Ibetti J, Chen SR, Chuprun JK, Hoek JB, Koch WJ, Hajnóczky G. Eisner V, et al. Among authors: cupo rr. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E859-E868. doi: 10.1073/pnas.1617288114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096338 Free PMC article.
Increased mitochondrial nanotunneling activity, induced by calcium imbalance, affects intermitochondrial matrix exchanges.
Lavorato M, Iyer VR, Dewight W, Cupo RR, Debattisti V, Gomez L, De la Fuente S, Zhao YT, Valdivia HH, Hajnóczky G, Franzini-Armstrong C. Lavorato M, et al. Among authors: cupo rr. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E849-E858. doi: 10.1073/pnas.1617788113. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096415 Free PMC article.
Tuning Hsp104 specificity to selectively detoxify α-synuclein.
Mack KL, Kim H, Barbieri EM, Lin J, Braganza S, Jackrel ME, DeNizio JE, Yan X, Chuang E, Tariq A, Cupo RR, Castellano LM, Caldwell KA, Caldwell GA, Shorter J. Mack KL, et al. Among authors: cupo rr. Mol Cell. 2023 Sep 21;83(18):3314-3332.e9. doi: 10.1016/j.molcel.2023.07.029. Epub 2023 Aug 24. Mol Cell. 2023. PMID: 37625404 Free PMC article.