Liu S - Search Results

1

Lipid Nanoparticle (LNP) Chemistry Can Endow Unique In Vivo RNA Delivery Fates within the Liver That Alter Therapeutic Outcomes in a Cancer Model.

Johnson LT, Zhang D, Zhou K, Lee SM, Liu S, Dilliard SA, Farbiak L, Chatterjee S, Lin YH, Siegwart DJ. Johnson LT, et al. Among authors: liu s. Mol Pharm. 2022 Nov 7;19(11):3973-3986. doi: 10.1021/acs.molpharmaceut.2c00442. Epub 2022 Sep 26. Mol Pharm. 2022. PMID: 36154076 Free PMC article.

2

Molecular flexibility and discontinuous translocation of a non-templated polymerase.

Johnson L, Liu S, Gershon PD. Johnson L, et al. Among authors: liu s. J Mol Biol. 2004 Apr 2;337(4):843-56. doi: 10.1016/j.jmb.2004.01.058. J Mol Biol. 2004. PMID: 15033355

3

Lipid-Modified Aminoglycosides for mRNA Delivery to the Liver.

Yu X, Liu S, Cheng Q, Wei T, Lee S, Zhang D, Siegwart DJ. Yu X, et al. Among authors: liu s. Adv Healthc Mater. 2020 Apr;9(7):e1901487. doi: 10.1002/adhm.201901487. Epub 2020 Feb 28. Adv Healthc Mater. 2020. PMID: 32108440 Free PMC article.

4

Theranostic dendrimer-based lipid nanoparticles containing PEGylated BODIPY dyes for tumor imaging and systemic mRNA delivery in vivo.

Xiong H, Liu S, Wei T, Cheng Q, Siegwart DJ. Xiong H, et al. Among authors: liu s. J Control Release. 2020 Sep 10;325:198-205. doi: 10.1016/j.jconrel.2020.06.030. Epub 2020 Jul 3. J Control Release. 2020. PMID: 32629133 Free PMC article.

5

A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo.

Lee SM, Cheng Q, Yu X, Liu S, Johnson LT, Siegwart DJ. Lee SM, et al. Among authors: liu s. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5848-5853. doi: 10.1002/anie.202013927. Epub 2021 Feb 1. Angew Chem Int Ed Engl. 2021. PMID: 33305471 Free PMC article.

6

Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR-Cas gene editing.

Liu S, Cheng Q, Wei T, Yu X, Johnson LT, Farbiak L, Siegwart DJ. Liu S, et al. Nat Mater. 2021 May;20(5):701-710. doi: 10.1038/s41563-020-00886-0. Epub 2021 Feb 4. Nat Mater. 2021. PMID: 33542471 Free PMC article.

7

Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration.

Yu X, Liu S, Cheng Q, Lee SM, Wei T, Zhang D, Farbiak L, Johnson LT, Wang X, Siegwart DJ. Yu X, et al. Among authors: liu s. Pharmaceutics. 2021 Nov 12;13(11):1914. doi: 10.3390/pharmaceutics13111914. Pharmaceutics. 2021. PMID: 34834329 Free PMC article.

8

Zwitterionic Phospholipidation of Cationic Polymers Facilitates Systemic mRNA Delivery to Spleen and Lymph Nodes.

Liu S, Wang X, Yu X, Cheng Q, Johnson LT, Chatterjee S, Zhang D, Lee SM, Sun Y, Lin TC, Liu JL, Siegwart DJ. Liu S, et al. Among authors: liu jl. J Am Chem Soc. 2021 Dec 22;143(50):21321-21330. doi: 10.1021/jacs.1c09822. Epub 2021 Dec 8. J Am Chem Soc. 2021. PMID: 34878786 Free PMC article.

9

An overview of lipid constituents in lipid nanoparticle mRNA delivery systems.

Wu S, Lin L, Shi L, Liu S. Wu S, et al. Among authors: liu s. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2024 Jul-Aug;16(4):e1978. doi: 10.1002/wnan.1978. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2024. PMID: 38965928 Review.

10

Reformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation.

Su K, Shi L, Sheng T, Yan X, Lin L, Meng C, Wu S, Chen Y, Zhang Y, Wang C, Wang Z, Qiu J, Zhao J, Xu T, Ping Y, Gu Z, Liu S. Su K, et al. Among authors: liu s. Nat Commun. 2024 Jul 5;15(1):5659. doi: 10.1038/s41467-024-50093-7. Nat Commun. 2024. PMID: 38969646 Free PMC article.

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