Springer TA - Search Results

1

A general chemical principle for creating closure-stabilizing integrin inhibitors.

Lin FY, Li J, Xie Y, Zhu J, Huong Nguyen TT, Zhang Y, Zhu J, Springer TA. Lin FY, et al. Among authors: springer ta. Cell. 2022 Sep 15;185(19):3533-3550.e27. doi: 10.1016/j.cell.2022.08.008. Cell. 2022. PMID: 36113427 Free PMC article.

2

Sequential regulation of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis.

Weber C, Alon R, Moser B, Springer TA. Weber C, et al. Among authors: springer ta. J Cell Biol. 1996 Aug;134(4):1063-73. doi: 10.1083/jcb.134.4.1063. J Cell Biol. 1996. PMID: 8769427 Free PMC article.

3

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling.

Takagi J, Petre BM, Walz T, Springer TA. Takagi J, et al. Among authors: springer ta. Cell. 2002 Sep 6;110(5):599-11. doi: 10.1016/s0092-8674(02)00935-2. Cell. 2002. PMID: 12230977 Free article.

4

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation.

Shimaoka M, Xiao T, Liu JH, Yang Y, Dong Y, Jun CD, McCormack A, Zhang R, Joachimiak A, Takagi J, Wang JH, Springer TA. Shimaoka M, et al. Among authors: springer ta. Cell. 2003 Jan 10;112(1):99-111. doi: 10.1016/s0092-8674(02)01257-6. Cell. 2003. PMID: 12526797 Free PMC article.

5

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand.

Luo BH, Springer TA, Takagi J. Luo BH, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2403-8. doi: 10.1073/pnas.0438060100. Epub 2003 Feb 25. Proc Natl Acad Sci U S A. 2003. PMID: 12604783 Free PMC article.

6

Tests of the extension and deadbolt models of integrin activation.

Zhu J, Boylan B, Luo BH, Newman PJ, Springer TA. Zhu J, et al. Among authors: springer ta. J Biol Chem. 2007 Apr 20;282(16):11914-20. doi: 10.1074/jbc.M700249200. Epub 2007 Feb 13. J Biol Chem. 2007. PMID: 17301049 Free PMC article.

7

Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. Zhu J, et al. Among authors: springer ta. Blood. 2007 Oct 1;110(7):2475-83. doi: 10.1182/blood-2007-03-080077. Epub 2007 Jul 5. Blood. 2007. PMID: 17615290 Free PMC article.

8

Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3.

Springer TA, Zhu J, Xiao T. Springer TA, et al. J Cell Biol. 2008 Aug 25;182(4):791-800. doi: 10.1083/jcb.200801146. Epub 2008 Aug 18. J Cell Biol. 2008. PMID: 18710925 Free PMC article.

9

Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces.

Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Zhu J, et al. Among authors: springer ta. Mol Cell. 2008 Dec 26;32(6):849-61. doi: 10.1016/j.molcel.2008.11.018. Mol Cell. 2008. PMID: 19111664 Free PMC article.

10

The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

Zhu J, Luo BH, Barth P, Schonbrun J, Baker D, Springer TA. Zhu J, et al. Among authors: springer ta. Mol Cell. 2009 Apr 24;34(2):234-49. doi: 10.1016/j.molcel.2009.02.022. Mol Cell. 2009. PMID: 19394300 Free PMC article.

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