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A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; GEMCAD 1602 study.
Español-Rego M, Fernández-Martos C, Elez E, Foguet C, Pedrosa L, Rodríguez N, Ruiz-Casado A, Pineda E, Cid J, Cabezón R, Oliveres H, Lozano M, Ginés A, García-Criado A, Ayuso JR, Pagés M, Cuatrecasas M, Torres F, Thomson T, Cascante M, Benítez-Ribas D, Maurel J. Español-Rego M, et al. Among authors: pedrosa l. Cancer Immunol Immunother. 2023 Apr;72(4):827-840. doi: 10.1007/s00262-022-03283-5. Epub 2022 Sep 9. Cancer Immunol Immunother. 2023. PMID: 36083313 Free PMC article.
The controversy of neoadjuvant therapy in rectal cancer.
Maurel J, Pedrosa L, Camps J. Maurel J, et al. Among authors: pedrosa l. Cir Esp (Engl Ed). 2019 Aug-Sep;97(7):361-363. doi: 10.1016/j.ciresp.2019.01.004. Epub 2019 Feb 14. Cir Esp (Engl Ed). 2019. PMID: 30773234 English, Spanish. No abstract available.
The Tumor Microenvironment in Colorectal Cancer Therapy.
Pedrosa L, Esposito F, Thomson TM, Maurel J. Pedrosa L, et al. Cancers (Basel). 2019 Aug 14;11(8):1172. doi: 10.3390/cancers11081172. Cancers (Basel). 2019. PMID: 31416205 Free PMC article. Review.
A novel gene signature unveils three distinct immune-metabolic rewiring patterns conserved across diverse tumor types and associated with outcomes.
Pedrosa L, Foguet C, Oliveres H, Archilla I, de Herreros MG, Rodríguez A, Postigo A, Benítez-Ribas D, Camps J, Cuatrecasas M, Castells A, Prat A, Thomson TM, Maurel J, Cascante M. Pedrosa L, et al. Front Immunol. 2022 Sep 2;13:926304. doi: 10.3389/fimmu.2022.926304. eCollection 2022. Front Immunol. 2022. PMID: 36119118 Free PMC article.
Mutational Status of SMAD4 and FBXW7 Affects Clinical Outcome in TP53-Mutated Metastatic Colorectal Cancer.
Lahoz S, Rodríguez A, Fernández L, Gorría T, Moreno R, Esposito F, Oliveres H, Albiol S, Saurí T, Pesantez D, Riu G, Cuatrecasas M, Jares P, Pedrosa L, Pineda E, Postigo A, Castells A, Prat A, Maurel J, Camps J. Lahoz S, et al. Among authors: pedrosa l. Cancers (Basel). 2022 Nov 30;14(23):5921. doi: 10.3390/cancers14235921. Cancers (Basel). 2022. PMID: 36497403 Free PMC article.
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy.
Pascual-García M, Bonfill-Teixidor E, Planas-Rigol E, Rubio-Perez C, Iurlaro R, Arias A, Cuartas I, Sala-Hojman A, Escudero L, Martínez-Ricarte F, Huber-Ruano I, Nuciforo P, Pedrosa L, Marques C, Braña I, Garralda E, Vieito M, Squatrito M, Pineda E, Graus F, Espejo C, Sahuquillo J, Tabernero J, Seoane J. Pascual-García M, et al. Among authors: pedrosa l. Nat Commun. 2019 Jun 11;10(1):2416. doi: 10.1038/s41467-019-10369-9. Nat Commun. 2019. PMID: 31186412 Free PMC article.
Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment.
Rubio-Perez C, Planas-Rigol E, Trincado JL, Bonfill-Teixidor E, Arias A, Marchese D, Moutinho C, Serna G, Pedrosa L, Iurlaro R, Martínez-Ricarte F, Escudero L, Cordero E, Cicuendez M, Ruiz S, Parra G, Nuciforo P, Gonzalez J, Pineda E, Sahuquillo J, Tabernero J, Heyn H, Seoane J. Rubio-Perez C, et al. Among authors: pedrosa l. Nat Commun. 2021 Mar 8;12(1):1503. doi: 10.1038/s41467-021-21789-x. Nat Commun. 2021. PMID: 33686071 Free PMC article.
GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma.
Moreno M, Pedrosa L, Paré L, Pineda E, Bejarano L, Martínez J, Balasubramaniyan V, Ezhilarasan R, Kallarackal N, Kim SH, Wang J, Audia A, Conroy S, Marin M, Ribalta T, Pujol T, Herreros A, Tortosa A, Mira H, Alonso MM, Gómez-Manzano C, Graus F, Sulman EP, Piao X, Nakano I, Prat A, Bhat KP, de la Iglesia N. Moreno M, et al. Among authors: pedrosa l. Cell Rep. 2017 Nov 21;21(8):2183-2197. doi: 10.1016/j.celrep.2017.10.083. Cell Rep. 2017. PMID: 29166609 Free article.
GRP94 promotes brain metastasis by engaging pro-survival autophagy.
Santana-Codina N, Muixí L, Foj R, Sanz-Pamplona R, Badia-Villanueva M, Abramowicz A, Marcé-Grau A, Cosialls AM, Gil J, Archilla I, Pedrosa L, Gonzalez J, Aldecoa I, Sierra A. Santana-Codina N, et al. Among authors: pedrosa l. Neuro Oncol. 2020 May 15;22(5):652-664. doi: 10.1093/neuonc/noz198. Neuro Oncol. 2020. PMID: 31637425 Free PMC article.
152 results