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A novel point mutation in the DNA-binding domain (DBD) of the human glucocorticoid receptor causes primary generalized glucocorticoid resistance by disrupting the hydrophobic structure of its DBD.
Roberts ML, Kino T, Nicolaides NC, Hurt DE, Katsantoni E, Sertedaki A, Komianou F, Kassiou K, Chrousos GP, Charmandari E. Roberts ML, et al. Among authors: sertedaki a. J Clin Endocrinol Metab. 2013 Apr;98(4):E790-5. doi: 10.1210/jc.2012-3549. Epub 2013 Feb 20. J Clin Endocrinol Metab. 2013. PMID: 23426617 Free PMC article.
A novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the p160 coactivators: dissociation of the transactivating and transreppressive activities.
Nicolaides NC, Roberts ML, Kino T, Braatvedt G, Hurt DE, Katsantoni E, Sertedaki A, Chrousos GP, Charmandari E. Nicolaides NC, et al. Among authors: sertedaki a. J Clin Endocrinol Metab. 2014 May;99(5):E902-7. doi: 10.1210/jc.2013-3005. Epub 2014 Jan 31. J Clin Endocrinol Metab. 2014. PMID: 24483153 Free PMC article.
Stress-induced Aldosterone Hyper-Secretion in a Substantial Subset of Patients With Essential Hypertension.
Markou A, Sertedaki A, Kaltsas G, Androulakis II, Marakaki C, Pappa T, Gouli A, Papanastasiou L, Fountoulakis S, Zacharoulis A, Karavidas A, Ragkou D, Charmandari E, Chrousos GP, Piaditis GP. Markou A, et al. Among authors: sertedaki a. J Clin Endocrinol Metab. 2015 Aug;100(8):2857-64. doi: 10.1210/jc.2015-1268. Epub 2015 May 14. J Clin Endocrinol Metab. 2015. PMID: 25974737
A novel mutation of the hGR gene causing Chrousos syndrome.
Nicolaides NC, Geer EB, Vlachakis D, Roberts ML, Psarra AM, Moutsatsou P, Sertedaki A, Kossida S, Charmandari E. Nicolaides NC, et al. Among authors: sertedaki a. Eur J Clin Invest. 2015 Aug;45(8):782-91. doi: 10.1111/eci.12470. Epub 2015 Jul 14. Eur J Clin Invest. 2015. PMID: 26031419
Transient generalized glucocorticoid hypersensitivity.
Nicolaides NC, Lamprokostopoulou A, Polyzos A, Kino T, Katsantoni E, Triantafyllou P, Christophoridis A, Katzos G, Dracopoulou M, Sertedaki A, Chrousos GP, Charmandari E. Nicolaides NC, et al. Among authors: sertedaki a. Eur J Clin Invest. 2015 Dec;45(12):1306-15. doi: 10.1111/eci.12554. Epub 2015 Nov 20. Eur J Clin Invest. 2015. PMID: 26479047
Functional characterization of the hGRαT556I causing Chrousos syndrome.
Nicolaides NC, Skyrla E, Vlachakis D, Psarra AM, Moutsatsou P, Sertedaki A, Kossida S, Charmandari E. Nicolaides NC, et al. Among authors: sertedaki a. Eur J Clin Invest. 2016 Jan;46(1):42-9. doi: 10.1111/eci.12563. Epub 2015 Dec 15. Eur J Clin Invest. 2016. PMID: 26541474
64 results