Wierenga ATJ - Search Results

1

Dietary methionine starvation impairs acute myeloid leukemia progression.

Cunningham A, Erdem A, Alshamleh I, Geugien M, Pruis M, Pereira-Martins DA, van den Heuvel FAJ, Wierenga ATJ, Ten Berge H, Dennebos R, van den Boom V, Hogeling SM, Weinhäuser I, Knops R, de Blaauw P, Heiner-Fokkema MR, Woolthuis C, Günther UL, Rego EM, Martens JHA, Jansen JH, Schwalbe H, Huls G, Schuringa JJ. Cunningham A, et al. Among authors: wierenga atj. Blood. 2022 Nov 10;140(19):2037-2052. doi: 10.1182/blood.2022017575. Blood. 2022. PMID: 35984907 Free article.

2

Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6.

Schuringa JJ, Wierenga AT, Kruijer W, Vellenga E. Schuringa JJ, et al. Blood. 2000 Jun 15;95(12):3765-70. Blood. 2000. PMID: 10845908 Free article.

3

Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-beta1 is mediated by caspase-dependent and -independent processes.

Wierenga AT, Schuringa JJ, Eggen BJ, Kruijer W, Vellenga E. Wierenga AT, et al. Leukemia. 2002 Apr;16(4):675-82. doi: 10.1038/sj.leu.2402425. Leukemia. 2002. PMID: 11960349

4

Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3.

Benus GF, Wierenga AT, de Gorter DJ, Schuringa JJ, van Bennekum AM, Drenth-Diephuis L, Vellenga E, Eggen BJ. Benus GF, et al. Mol Biol Cell. 2005 Aug;16(8):3501-10. doi: 10.1091/mbc.e04-11-1033. Epub 2005 May 25. Mol Biol Cell. 2005. PMID: 15917296 Free PMC article.

5

STAT5-induced self-renewal and impaired myelopoiesis of human hematopoietic stem/progenitor cells involves down-modulation of C/EBPalpha.

Wierenga AT, Schepers H, Moore MA, Vellenga E, Schuringa JJ. Wierenga AT, et al. Blood. 2006 Jun 1;107(11):4326-33. doi: 10.1182/blood-2005-11-4608. Epub 2006 Feb 2. Blood. 2006. PMID: 16455947 Free article.

6

Reintroduction of C/EBPalpha in leukemic CD34+ stem/progenitor cells impairs self-renewal and partially restores myelopoiesis.

Schepers H, Wierenga AT, van Gosliga D, Eggen BJ, Vellenga E, Schuringa JJ. Schepers H, et al. Blood. 2007 Aug 15;110(4):1317-25. doi: 10.1182/blood-2006-10-052175. Epub 2007 May 2. Blood. 2007. PMID: 17475913 Free article.

7

STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells.

Schepers H, van Gosliga D, Wierenga AT, Eggen BJ, Schuringa JJ, Vellenga E. Schepers H, et al. Blood. 2007 Oct 15;110(8):2880-8. doi: 10.1182/blood-2006-08-039073. Epub 2007 Jul 13. Blood. 2007. PMID: 17630355 Free article.

8

Maximal STAT5-induced proliferation and self-renewal at intermediate STAT5 activity levels.

Wierenga AT, Vellenga E, Schuringa JJ. Wierenga AT, et al. Mol Cell Biol. 2008 Nov;28(21):6668-80. doi: 10.1128/MCB.01025-08. Epub 2008 Sep 8. Mol Cell Biol. 2008. PMID: 18779318 Free PMC article.

9

Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses.

Han L, Wierenga AT, Rozenveld-Geugien M, van de Lande K, Vellenga E, Schuringa JJ. Han L, et al. PLoS One. 2009 Nov 24;4(11):e7989. doi: 10.1371/journal.pone.0007989. PLoS One. 2009. PMID: 19956772 Free PMC article.

10

Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation.

Wierenga AT, Vellenga E, Schuringa JJ. Wierenga AT, et al. Blood. 2010 Jun 3;115(22):4367-76. doi: 10.1182/blood-2009-10-250894. Epub 2010 Mar 25. Blood. 2010. PMID: 20339093 Free article.

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