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MYB orchestrates T cell exhaustion and response to checkpoint inhibition.
Tsui C, Kretschmer L, Rapelius S, Gabriel SS, Chisanga D, Knöpper K, Utzschneider DT, Nüssing S, Liao Y, Mason T, Torres SV, Wilcox SA, Kanev K, Jarosch S, Leube J, Nutt SL, Zehn D, Parish IA, Kastenmüller W, Shi W, Buchholz VR, Kallies A. Tsui C, et al. Among authors: utzschneider dt. Nature. 2022 Sep;609(7926):354-360. doi: 10.1038/s41586-022-05105-1. Epub 2022 Aug 17. Nature. 2022. PMID: 35978192 Free PMC article.
Functional avidity: a measure to predict the efficacy of effector T cells?
Viganò S, Utzschneider DT, Perreau M, Pantaleo G, Zehn D, Harari A. Viganò S, et al. Among authors: utzschneider dt. Clin Dev Immunol. 2012;2012:153863. doi: 10.1155/2012/153863. Epub 2012 Nov 20. Clin Dev Immunol. 2012. PMID: 23227083 Free PMC article. Review.
Immune-surveillance through exhausted effector T-cells.
Zehn D, Utzschneider DT, Thimme R. Zehn D, et al. Among authors: utzschneider dt. Curr Opin Virol. 2016 Feb;16:49-54. doi: 10.1016/j.coviro.2016.01.002. Epub 2016 Jan 29. Curr Opin Virol. 2016. PMID: 26826950 Review.
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Alfei F, Kanev K, Hofmann M, Wu M, Ghoneim HE, Roelli P, Utzschneider DT, von Hoesslin M, Cullen JG, Fan Y, Eisenberg V, Wohlleber D, Steiger K, Merkler D, Delorenzi M, Knolle PA, Cohen CJ, Thimme R, Youngblood B, Zehn D. Alfei F, et al. Among authors: utzschneider dt. Nature. 2019 Jul;571(7764):265-269. doi: 10.1038/s41586-019-1326-9. Epub 2019 Jun 17. Nature. 2019. PMID: 31207605
Precursor exhausted T cells: key to successful immunotherapy?
Kallies A, Zehn D, Utzschneider DT. Kallies A, et al. Among authors: utzschneider dt. Nat Rev Immunol. 2020 Feb;20(2):128-136. doi: 10.1038/s41577-019-0223-7. Epub 2019 Oct 7. Nat Rev Immunol. 2020. PMID: 31591533 Review.
32 results