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MYB orchestrates T cell exhaustion and response to checkpoint inhibition.
Tsui C, Kretschmer L, Rapelius S, Gabriel SS, Chisanga D, Knöpper K, Utzschneider DT, Nüssing S, Liao Y, Mason T, Torres SV, Wilcox SA, Kanev K, Jarosch S, Leube J, Nutt SL, Zehn D, Parish IA, Kastenmüller W, Shi W, Buchholz VR, Kallies A. Tsui C, et al. Among authors: kastenmuller w. Nature. 2022 Sep;609(7926):354-360. doi: 10.1038/s41586-022-05105-1. Epub 2022 Aug 17. Nature. 2022. PMID: 35978192 Free PMC article.
Functional classification of memory CD8(+) T cells by CX3CR1 expression.
Böttcher JP, Beyer M, Meissner F, Abdullah Z, Sander J, Höchst B, Eickhoff S, Rieckmann JC, Russo C, Bauer T, Flecken T, Giesen D, Engel D, Jung S, Busch DH, Protzer U, Thimme R, Mann M, Kurts C, Schultze JL, Kastenmüller W, Knolle PA. Böttcher JP, et al. Among authors: kastenmuller w. Nat Commun. 2015 Sep 25;6:8306. doi: 10.1038/ncomms9306. Nat Commun. 2015. PMID: 26404698 Free PMC article.
CD4+ T cell help in cancer immunology and immunotherapy.
Borst J, Ahrends T, Bąbała N, Melief CJM, Kastenmüller W. Borst J, et al. Among authors: kastenmuller w. Nat Rev Immunol. 2018 Oct;18(10):635-647. doi: 10.1038/s41577-018-0044-0. Nat Rev Immunol. 2018. PMID: 30057419 Review.
Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis.
Welz M, Eickhoff S, Abdullah Z, Trebicka J, Gartlan KH, Spicer JA, Demetris AJ, Akhlaghi H, Anton M, Manske K, Zehn D, Nieswandt B, Kurts C, Trapani JA, Knolle P, Wohlleber D, Kastenmüller W. Welz M, et al. Among authors: kastenmuller w. Nat Commun. 2018 Nov 15;9(1):4805. doi: 10.1038/s41467-018-07213-x. Nat Commun. 2018. PMID: 30442932 Free PMC article.
Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells.
Bachem A, Makhlouf C, Binger KJ, de Souza DP, Tull D, Hochheiser K, Whitney PG, Fernandez-Ruiz D, Dähling S, Kastenmüller W, Jönsson J, Gressier E, Lew AM, Perdomo C, Kupz A, Figgett W, Mackay F, Oleshansky M, Russ BE, Parish IA, Kallies A, McConville MJ, Turner SJ, Gebhardt T, Bedoui S. Bachem A, et al. Among authors: kastenmuller w. Immunity. 2019 Aug 20;51(2):285-297.e5. doi: 10.1016/j.immuni.2019.06.002. Epub 2019 Jul 1. Immunity. 2019. PMID: 31272808 Free article.
BATF3 programs CD8+ T cell memory.
Ataide MA, Komander K, Knöpper K, Peters AE, Wu H, Eickhoff S, Gogishvili T, Weber J, Grafen A, Kallies A, Garbi N, Einsele H, Hudecek M, Gasteiger G, Hölzel M, Vaeth M, Kastenmüller W. Ataide MA, et al. Among authors: kastenmuller w. Nat Immunol. 2020 Nov;21(11):1397-1407. doi: 10.1038/s41590-020-0786-2. Epub 2020 Sep 28. Nat Immunol. 2020. PMID: 32989328
Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues.
Friedrich C, Taggenbrock RLRE, Doucet-Ladevèze R, Golda G, Moenius R, Arampatzi P, Kragten NAM, Kreymborg K, Gomez de Agüero M, Kastenmüller W, Saliba AE, Grün D, van Gisbergen KPJM, Gasteiger G. Friedrich C, et al. Among authors: kastenmuller w. Nat Immunol. 2021 Oct;22(10):1256-1267. doi: 10.1038/s41590-021-01013-0. Epub 2021 Aug 30. Nat Immunol. 2021. PMID: 34462601 Free PMC article.
A multifunctional mouse model to study the role of Samd3.
Peters AE, Knöpper K, Grafen A, Kastenmüller W. Peters AE, et al. Among authors: kastenmuller w. Eur J Immunol. 2022 Feb;52(2):328-337. doi: 10.1002/eji.202149469. Epub 2021 Nov 7. Eur J Immunol. 2022. PMID: 34626120 Free article.
74 results