MacLean RC - Search Results

1

Pre-existing chromosomal polymorphisms in pathogenic E. coli potentiate the evolution of resistance to a last-resort antibiotic.

Jangir PK, Yang Q, Shaw LP, Caballero JD, Ogunlana L, Wheatley R, Walsh T, MacLean RC. Jangir PK, et al. Among authors: maclean rc. Elife. 2022 Aug 9;11:e78834. doi: 10.7554/eLife.78834. Elife. 2022. PMID: 35943060 Free PMC article.

2

The evolution of antibiotic resistance: insight into the roles of molecular mechanisms of resistance and treatment context.

Maclean RC, Hall AR, Perron GG, Buckling A. Maclean RC, et al. Discov Med. 2010 Aug;10(51):112-8. Discov Med. 2010. PMID: 20807471 Free article. Review.

3

Persistence and resistance as complementary bacterial adaptations to antibiotics.

Vogwill T, Comfort AC, Furió V, MacLean RC. Vogwill T, et al. Among authors: maclean rc. J Evol Biol. 2016 Jun;29(6):1223-33. doi: 10.1111/jeb.12864. Epub 2016 Apr 6. J Evol Biol. 2016. PMID: 26999656 Free PMC article.

4

Identifying and exploiting genes that potentiate the evolution of antibiotic resistance.

Gifford DR, Furió V, Papkou A, Vogwill T, Oliver A, MacLean RC. Gifford DR, et al. Among authors: maclean rc. Nat Ecol Evol. 2018 Jun;2(6):1033-1039. doi: 10.1038/s41559-018-0547-x. Epub 2018 Apr 23. Nat Ecol Evol. 2018. PMID: 29686236 Free PMC article.

5

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance.

Escudero JA, MacLean RC, San Millan A. Escudero JA, et al. Among authors: maclean rc. J Vis Exp. 2018 May 2;(135):57386. doi: 10.3791/57386. J Vis Exp. 2018. PMID: 29781985 Free PMC article.

6

Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells.

Alexander HK, MacLean RC. Alexander HK, et al. Among authors: maclean rc. Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):19455-19464. doi: 10.1073/pnas.1919672117. Epub 2020 Jul 23. Proc Natl Acad Sci U S A. 2020. PMID: 32703812 Free PMC article.

7

Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates.

Papkou A, Hedge J, Kapel N, Young B, MacLean RC. Papkou A, et al. Among authors: maclean rc. Nat Commun. 2020 Aug 7;11(1):3970. doi: 10.1038/s41467-020-17735-y. Nat Commun. 2020. PMID: 32769975 Free PMC article.

8

CRISPR-Cas systems restrict horizontal gene transfer in Pseudomonas aeruginosa.

Wheatley RM, MacLean RC. Wheatley RM, et al. Among authors: maclean rc. ISME J. 2021 May;15(5):1420-1433. doi: 10.1038/s41396-020-00860-3. Epub 2020 Dec 21. ISME J. 2021. PMID: 33349652 Free PMC article.

9

Integron activity accelerates the evolution of antibiotic resistance.

Souque C, Escudero JA, MacLean RC. Souque C, et al. Among authors: maclean rc. Elife. 2021 Feb 26;10:e62474. doi: 10.7554/eLife.62474. Elife. 2021. PMID: 33634790 Free PMC article.

10

Evolutionary constraints on the acquisition of antimicrobial peptide resistance in bacterial pathogens.

Jangir PK, Ogunlana L, MacLean RC. Jangir PK, et al. Among authors: maclean rc. Trends Microbiol. 2021 Dec;29(12):1058-1061. doi: 10.1016/j.tim.2021.03.007. Epub 2021 Apr 6. Trends Microbiol. 2021. PMID: 33836929

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