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JNK pathway plays a critical role for expansion of human colorectal cancer in the context of BRG1 suppression.
Yoshikawa T, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Kawada K, Takaishi S, Seno H. Yoshikawa T, et al. Among authors: araki o. Cancer Sci. 2022 Oct;113(10):3417-3427. doi: 10.1111/cas.15520. Epub 2022 Aug 17. Cancer Sci. 2022. PMID: 35924439 Free PMC article.
Brg1 is required to maintain colorectal cancer stem cells.
Yoshikawa T, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Kawada K, Takaishi S, Seno H. Yoshikawa T, et al. Among authors: araki o. J Pathol. 2021 Nov;255(3):257-269. doi: 10.1002/path.5759. Epub 2021 Aug 20. J Pathol. 2021. PMID: 34415580
Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice.
Nagao M, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Yoshikawa T, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Taketo MM, Ferrer J, Tsuruyama T, Nakanuma Y, Taura K, Uemoto S, Seno H. Nagao M, et al. Among authors: araki o. Cancer Res. 2022 May 3;82(9):1803-1817. doi: 10.1158/0008-5472.CAN-21-2176. Cancer Res. 2022. PMID: 35247892
ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H. Kimura Y, et al. Among authors: araki o. Gastroenterology. 2018 Jul;155(1):194-209.e2. doi: 10.1053/j.gastro.2018.03.039. Epub 2018 Mar 29. Gastroenterology. 2018. PMID: 29604291
Epithelial EP4 plays an essential role in maintaining homeostasis in colon.
Matsumoto Y, Nakanishi Y, Yoshioka T, Yamaga Y, Masuda T, Fukunaga Y, Sono M, Yoshikawa T, Nagao M, Araki O, Ogawa S, Goto N, Hiramatsu Y, Breyer RM, Fukuda A, Seno H. Matsumoto Y, et al. Among authors: araki o. Sci Rep. 2019 Oct 23;9(1):15244. doi: 10.1038/s41598-019-51639-2. Sci Rep. 2019. PMID: 31645712 Free PMC article.
SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice.
Ogawa S, Fukuda A, Matsumoto Y, Hanyu Y, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Yoshikawa T, Goto N, Hiramatsu Y, Tsuda M, Maruno T, Nakanishi Y, Hussein MS, Tsuruyama T, Takaori K, Uemoto S, Seno H. Ogawa S, et al. Among authors: araki o. Gastroenterology. 2020 Aug;159(2):682-696.e13. doi: 10.1053/j.gastro.2020.04.047. Epub 2020 Apr 28. Gastroenterology. 2020. PMID: 32360551 Free article.
Loss of Arid1a and Pten in Pancreatic Ductal Cells Induces Intraductal Tubulopapillary Neoplasm via the YAP/TAZ Pathway.
Fukunaga Y, Fukuda A, Omatsu M, Namikawa M, Sono M, Masuda T, Araki O, Nagao M, Yoshikawa T, Ogawa S, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Ferrer J, Tsuruyama T, Masui T, Hatano E, Seno H. Fukunaga Y, et al. Among authors: araki o. Gastroenterology. 2022 Aug;163(2):466-480.e6. doi: 10.1053/j.gastro.2022.04.020. Epub 2022 Apr 25. Gastroenterology. 2022. PMID: 35483445
Bmi1 marks gastric stem cells located in the isthmus in mice.
Yoshioka T, Fukuda A, Araki O, Ogawa S, Hanyu Y, Matsumoto Y, Yamaga Y, Nakanishi Y, Kawada K, Sakai Y, Chiba T, Seno H. Yoshioka T, et al. Among authors: araki o. J Pathol. 2019 Jun;248(2):179-190. doi: 10.1002/path.5244. Epub 2019 Feb 20. J Pathol. 2019. PMID: 30689202
150 results