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A non-canonical vitamin K cycle is a potent ferroptosis suppressor.
Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, Tonnus W, Nepachalovich P, Eggenhofer E, Aldrovandi M, Henkelmann B, Yamada KI, Wanninger J, Zilka O, Sato E, Feederle R, Hass D, Maida A, Mourão ASD, Linkermann A, Geissler EK, Nakagawa K, Abe T, Fedorova M, Proneth B, Pratt DA, Conrad M. Mishima E, et al. Among authors: pratt da. Nature. 2022 Aug;608(7924):778-783. doi: 10.1038/s41586-022-05022-3. Epub 2022 Aug 3. Nature. 2022. PMID: 35922516 Free PMC article.
Ferroptosis Inhibition: Mechanisms and Opportunities.
Angeli JPF, Shah R, Pratt DA, Conrad M. Angeli JPF, et al. Among authors: pratt da. Trends Pharmacol Sci. 2017 May;38(5):489-498. doi: 10.1016/j.tips.2017.02.005. Epub 2017 Mar 28. Trends Pharmacol Sci. 2017. PMID: 28363764 Review.
FSP1 is a glutathione-independent ferroptosis suppressor.
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius E, Scheel CH, Mourão A, Buday K, Sato M, Wanninger J, Vignane T, Mohana V, Rehberg M, Flatley A, Schepers A, Kurz A, White D, Sauer M, Sattler M, Tate EW, Schmitz W, Schulze A, O'Donnell V, Proneth B, Popowicz GM, Pratt DA, Angeli JPF, Conrad M. Doll S, et al. Among authors: pratt da, da silva mc. Nature. 2019 Nov;575(7784):693-698. doi: 10.1038/s41586-019-1707-0. Epub 2019 Oct 21. Nature. 2019. PMID: 31634899
The chemical basis of ferroptosis.
Conrad M, Pratt DA. Conrad M, et al. Among authors: pratt da. Nat Chem Biol. 2019 Dec;15(12):1137-1147. doi: 10.1038/s41589-019-0408-1. Epub 2019 Nov 18. Nat Chem Biol. 2019. PMID: 31740834 Review.
159 results