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A non-canonical vitamin K cycle is a potent ferroptosis suppressor.
Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, Tonnus W, Nepachalovich P, Eggenhofer E, Aldrovandi M, Henkelmann B, Yamada KI, Wanninger J, Zilka O, Sato E, Feederle R, Hass D, Maida A, Mourão ASD, Linkermann A, Geissler EK, Nakagawa K, Abe T, Fedorova M, Proneth B, Pratt DA, Conrad M. Mishima E, et al. Among authors: linkermann a. Nature. 2022 Aug;608(7924):778-783. doi: 10.1038/s41586-022-05022-3. Epub 2022 Aug 3. Nature. 2022. PMID: 35922516 Free PMC article.
The in vivo evidence for regulated necrosis.
Tonnus W, Linkermann A. Tonnus W, et al. Among authors: linkermann a. Immunol Rev. 2017 May;277(1):128-149. doi: 10.1111/imr.12551. Immunol Rev. 2017. PMID: 28462528 Review.
Die later with ESCRT!
Tonnus W, Gembardt F, Hugo C, Linkermann A. Tonnus W, et al. Among authors: linkermann a. Oncotarget. 2017 Jun 27;8(26):41790-41791. doi: 10.18632/oncotarget.17903. Oncotarget. 2017. PMID: 28574845 Free PMC article. No abstract available.
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD. Stockwell BR, et al. Among authors: linkermann a. Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Cell. 2017. PMID: 28985560 Free PMC article. Review.
Origin and Consequences of Necroinflammation.
Sarhan M, Land WG, Tonnus W, Hugo CP, Linkermann A. Sarhan M, et al. Among authors: linkermann a. Physiol Rev. 2018 Apr 1;98(2):727-780. doi: 10.1152/physrev.00041.2016. Physiol Rev. 2018. PMID: 29465288 Free article. Review.
154 results