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Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity.
Backlund CM, Holden RL, Moynihan KD, Garafola D, Farquhar C, Mehta NK, Maiorino L, Pham S, Iorgulescu JB, Reardon DA, Wu CJ, Pentelute BL, Irvine DJ. Backlund CM, et al. Among authors: moynihan kd. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204078119. doi: 10.1073/pnas.2204078119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914154 Free PMC article.
Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.
Zhu EF, Gai SA, Opel CF, Kwan BH, Surana R, Mihm MC, Kauke MJ, Moynihan KD, Angelini A, Williams RT, Stephan MT, Kim JS, Yaffe MB, Irvine DJ, Weiner LM, Dranoff G, Wittrup KD. Zhu EF, et al. Among authors: moynihan kd. Cancer Cell. 2015 Apr 13;27(4):489-501. doi: 10.1016/j.ccell.2015.03.004. Cancer Cell. 2015. PMID: 25873172 Free PMC article.
Engineering New Approaches to Cancer Vaccines.
Mehta NK, Moynihan KD, Irvine DJ. Mehta NK, et al. Among authors: moynihan kd. Cancer Immunol Res. 2015 Aug;3(8):836-43. doi: 10.1158/2326-6066.CIR-15-0112. Epub 2015 Jul 8. Cancer Immunol Res. 2015. PMID: 26156157 Free PMC article. Review.
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
Moynihan KD, Opel CF, Szeto GL, Tzeng A, Zhu EF, Engreitz JM, Williams RT, Rakhra K, Zhang MH, Rothschilds AM, Kumari S, Kelly RL, Kwan BH, Abraham W, Hu K, Mehta NK, Kauke MJ, Suh H, Cochran JR, Lauffenburger DA, Wittrup KD, Irvine DJ. Moynihan KD, et al. Nat Med. 2016 Dec;22(12):1402-1410. doi: 10.1038/nm.4200. Epub 2016 Oct 24. Nat Med. 2016. PMID: 27775706 Free PMC article.
Roles for Innate Immunity in Combination Immunotherapies.
Moynihan KD, Irvine DJ. Moynihan KD, et al. Cancer Res. 2017 Oct 1;77(19):5215-5221. doi: 10.1158/0008-5472.CAN-17-1340. Epub 2017 Sep 19. Cancer Res. 2017. PMID: 28928130 Free PMC article. Review.
28 results