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Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity.
Backlund CM, Holden RL, Moynihan KD, Garafola D, Farquhar C, Mehta NK, Maiorino L, Pham S, Iorgulescu JB, Reardon DA, Wu CJ, Pentelute BL, Irvine DJ. Backlund CM, et al. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204078119. doi: 10.1073/pnas.2204078119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914154 Free PMC article.
Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer.
Westcott PMK, Sacks NJ, Schenkel JM, Ely ZA, Smith O, Hauck H, Jaeger AM, Zhang D, Backlund CM, Beytagh MC, Patten JJ, Elbashir R, Eng G, Irvine DJ, Yilmaz OH, Jacks T. Westcott PMK, et al. Among authors: backlund cm. Nat Cancer. 2021 Oct;2(10):1071-1085. doi: 10.1038/s43018-021-00247-z. Epub 2021 Sep 30. Nat Cancer. 2021. PMID: 34738089 Free PMC article.
Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma.
Grace BE, Backlund CM, Morgan DM, Kang BH, Singh NK, Huisman BD, Rappazzo CG, Moynihan KD, Maiorino L, Dobson CS, Kyung T, Gordon KS, Holec PV, Mbah OCT, Garafola D, Wu S, Love JC, Wittrup KD, Irvine DJ, Birnbaum ME. Grace BE, et al. Among authors: backlund cm. Front Immunol. 2022 Jun 23;13:886683. doi: 10.3389/fimmu.2022.886683. eCollection 2022. Front Immunol. 2022. PMID: 35812387 Free PMC article.
Biomaterials-Mediated Engineering of the Immune System.
Backlund C, Jalili-Firoozinezhad S, Kim B, Irvine DJ. Backlund C, et al. Annu Rev Immunol. 2023 Apr 26;41:153-179. doi: 10.1146/annurev-immunol-101721-040259. Epub 2023 Jan 25. Annu Rev Immunol. 2023. PMID: 36696570 Free PMC article. Review.
17 results