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Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Su Y, Wei W, Robert L, Xue M, Tsoi J, Garcia-Diaz A, Homet Moreno B, Kim J, Ng RH, Lee JW, Koya RC, Comin-Anduix B, Graeber TG, Ribas A, Heath JR. Su Y, et al. Among authors: lee jw. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13679-13684. doi: 10.1073/pnas.1712064115. Epub 2017 Dec 11. Proc Natl Acad Sci U S A. 2017. PMID: 29229836 Free PMC article.
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line.
Su Y, Ko ME, Cheng H, Zhu R, Xue M, Wang J, Lee JW, Frankiw L, Xu A, Wong S, Robert L, Takata K, Yuan D, Lu Y, Huang S, Ribas A, Levine R, Nolan GP, Wei W, Plevritis SK, Li G, Baltimore D, Heath JR. Su Y, et al. Among authors: lee jw. Nat Commun. 2020 May 11;11(1):2345. doi: 10.1038/s41467-020-15956-9. Nat Commun. 2020. PMID: 32393797 Free PMC article.
Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19.
Lee JW, Su Y, Baloni P, Chen D, Pavlovitch-Bedzyk AJ, Yuan D, Duvvuri VR, Ng RH, Choi J, Xie J, Zhang R, Murray K, Kornilov S, Smith B, Magis AT, Hoon DSB, Hadlock JJ, Goldman JD, Price ND, Gottardo R, Davis MM, Hood L, Greenberg PD, Heath JR. Lee JW, et al. Nat Biotechnol. 2022 Jan;40(1):110-120. doi: 10.1038/s41587-021-01020-4. Epub 2021 Sep 6. Nat Biotechnol. 2022. PMID: 34489601 Free PMC article.
Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity.
Lee JW, Chen EY, Hu T, Perret R, Chaffee ME, Martinov T, Mureli S, McCurdy CL, Jones LA, Gafken PR, Chanana P, Su Y, Chapuis AG, Bradley P, Schmitt TM, Greenberg PD. Lee JW, et al. bioRxiv [Preprint]. 2024 Oct 14:2024.09.18.612965. doi: 10.1101/2024.09.18.612965. bioRxiv. 2024. PMID: 39345486 Free PMC article. Preprint.
Pilot Trial of Perampanel on Peritumoral Hyperexcitability in Newly Diagnosed High-grade Glioma.
Tobochnik S, Regan MS, Dorotan MKC, Reich D, Lapinskas E, Hossain MA, Stopka S, Meredith DM, Santagata S, Murphy MM, Arnaout O, Bi WL, Chiocca EA, Golby AJ, Mooney MA, Smith TR, Ligon KL, Wen PY, Agar NYR, Lee JW. Tobochnik S, et al. Among authors: lee jw. Clin Cancer Res. 2024 Nov 5:OF1-OF9. doi: 10.1158/1078-0432.CCR-24-1849. Online ahead of print. Clin Cancer Res. 2024. PMID: 39499201
8,837 results