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Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Su Y, Wei W, Robert L, Xue M, Tsoi J, Garcia-Diaz A, Homet Moreno B, Kim J, Ng RH, Lee JW, Koya RC, Comin-Anduix B, Graeber TG, Ribas A, Heath JR. Su Y, et al. Among authors: heath jr. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13679-13684. doi: 10.1073/pnas.1712064115. Epub 2017 Dec 11. Proc Natl Acad Sci U S A. 2017. PMID: 29229836 Free PMC article.
A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication.
Zhou J, Bethune MT, Malkova N, Sutherland AM, Comin-Anduix B, Su Y, Baltimore D, Ribas A, Heath JR. Zhou J, et al. Among authors: heath jr. PLoS One. 2018 Jan 23;13(1):e0191634. doi: 10.1371/journal.pone.0191634. eCollection 2018. PLoS One. 2018. PMID: 29360859 Free PMC article.
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line.
Su Y, Ko ME, Cheng H, Zhu R, Xue M, Wang J, Lee JW, Frankiw L, Xu A, Wong S, Robert L, Takata K, Yuan D, Lu Y, Huang S, Ribas A, Levine R, Nolan GP, Wei W, Plevritis SK, Li G, Baltimore D, Heath JR. Su Y, et al. Among authors: heath jr. Nat Commun. 2020 May 11;11(1):2345. doi: 10.1038/s41467-020-15956-9. Nat Commun. 2020. PMID: 32393797 Free PMC article.
Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories.
Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, Xu A, Li J, Dong S, Rothchild A, Zhou J, Murray K, Edmark R, Hong S, Jones L, Zhou Y, Roper R, Mackay S, O'Mahony DS, Dale CR, Wallick JA, Algren HA, Michael ZA, Magis A, Wei W, Price ND, Huang S, Subramanian N, Wang K, Hadlock J, Hood L, Aderem A, Bluestone JA, Lanier LL, Greenberg P, Gottardo R, Davis MM, Goldman JD, Heath JR. Su Y, et al. Among authors: heath jr. bioRxiv [Preprint]. 2020 Jul 31:2020.07.27.224063. doi: 10.1101/2020.07.27.224063. bioRxiv. 2020. PMID: 32766585 Free PMC article. Preprint.
472 results