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Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor.
Kleist AB, Jenjak S, Sente A, Laskowski LJ, Szpakowska M, Calkins MM, Anderson EI, McNally LM, Heukers R, Bobkov V, Peterson FC, Thomas MA, Chevigné A, Smit MJ, McCorvy JD, Babu MM, Volkman BF. Kleist AB, et al. Among authors: chevigne a. Science. 2022 Jul 8;377(6602):222-228. doi: 10.1126/science.abj4922. Epub 2022 Jul 7. Science. 2022. PMID: 35857540 Free PMC article.
vCCL2/vMIP-II, the viral master KEYmokine.
Szpakowska M, Chevigné A. Szpakowska M, et al. Among authors: chevigne a. J Leukoc Biol. 2016 Jun;99(6):893-900. doi: 10.1189/jlb.2MR0815-383R. Epub 2015 Dec 23. J Leukoc Biol. 2016. PMID: 26701133 Review.
Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3.
Szpakowska M, Nevins AM, Meyrath M, Rhainds D, D'huys T, Guité-Vinet F, Dupuis N, Gauthier PA, Counson M, Kleist A, St-Onge G, Hanson J, Schols D, Volkman BF, Heveker N, Chevigné A. Szpakowska M, et al. Among authors: chevigne a. Br J Pharmacol. 2018 May;175(9):1419-1438. doi: 10.1111/bph.14132. Epub 2018 Mar 23. Br J Pharmacol. 2018. PMID: 29272550 Free PMC article.
83 results