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Page 1
Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression.
Zagozewski J, Borlase S, Guppy BJ, Coudière-Morrison L, Shahriary GM, Gordon V, Liang L, Cheng S, Porter CJ, Kelley R, Hawkins C, Chan JA, Liang Y, Gong J, Nör C, Saulnier O, Wechsler-Reya RJ, Ramaswamy V, Werbowetski-Ogilvie TE. Zagozewski J, et al. Commun Biol. 2022 Jul 14;5(1):697. doi: 10.1038/s42003-022-03654-9. Commun Biol. 2022. PMID: 35835937 Free PMC article.
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.
Zagozewski J, Shahriary GM, Morrison LC, Saulnier O, Stromecki M, Fresnoza A, Palidwor G, Porter CJ, Forget A, Ayrault O, Hawkins C, Chan JA, Vladoiu MC, Sundaresan L, Arsenio J, Taylor MD, Ramaswamy V, Werbowetski-Ogilvie TE. Zagozewski J, et al. Nat Commun. 2020 Jul 20;11(1):3627. doi: 10.1038/s41467-020-17357-4. Nat Commun. 2020. PMID: 32686664 Free PMC article.
Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma.
Martell E, Kuzmychova H, Kaul E, Senthil H, Chowdhury SR, Morrison LC, Fresnoza A, Zagozewski J, Venugopal C, Anderson CM, Singh SK, Banerji V, Werbowetski-Ogilvie TE, Sharif T. Martell E, et al. Among authors: zagozewski j. Nat Commun. 2023 May 2;14(1):2502. doi: 10.1038/s41467-023-38049-9. Nat Commun. 2023. PMID: 37130865 Free PMC article.
The role of homeobox genes in retinal development and disease.
Zagozewski JL, Zhang Q, Pinto VI, Wigle JT, Eisenstat DD. Zagozewski JL, et al. Dev Biol. 2014 Sep 15;393(2):195-208. doi: 10.1016/j.ydbio.2014.07.004. Epub 2014 Jul 15. Dev Biol. 2014. PMID: 25035933 Free article. Review.
Genetic regulation of vertebrate eye development.
Zagozewski JL, Zhang Q, Eisenstat DD. Zagozewski JL, et al. Clin Genet. 2014 Nov;86(5):453-60. doi: 10.1111/cge.12493. Epub 2014 Sep 25. Clin Genet. 2014. PMID: 25174583 Review.
GABAergic Interneuron Differentiation in the Basal Forebrain Is Mediated through Direct Regulation of Glutamic Acid Decarboxylase Isoforms by Dlx Homeobox Transcription Factors.
Le TN, Zhou QP, Cobos I, Zhang S, Zagozewski J, Japoni S, Vriend J, Parkinson T, Du G, Rubenstein JL, Eisenstat DD. Le TN, et al. Among authors: zagozewski j. J Neurosci. 2017 Sep 6;37(36):8816-8829. doi: 10.1523/JNEUROSCI.2125-16.2017. Epub 2017 Aug 8. J Neurosci. 2017. PMID: 28821666 Free PMC article.
A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing.
Saulnier O, Zagozewski J, Liang L, Hendrikse LD, Layug P, Gordon V, Aldinger KA, Haldipur P, Borlase S, Coudière-Morrison L, Cai T, Martell E, Gonzales NM, Palidwor G, Porter CJ, Richard S, Sharif T, Millen KJ, Doble BW, Taylor MD, Werbowetski-Ogilvie TE. Saulnier O, et al. Among authors: zagozewski j. Nat Cell Biol. 2024 Aug;26(8):1233-1246. doi: 10.1038/s41556-024-01460-5. Epub 2024 Jul 18. Nat Cell Biol. 2024. PMID: 39025928 Free PMC article.