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Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension.
Rinschen MM, Palygin O, El-Meanawy A, Domingo-Almenara X, Palermo A, Dissanayake LV, Golosova D, Schafroth MA, Guijas C, Demir F, Jaegers J, Gliozzi ML, Xue J, Hoehne M, Benzing T, Kok BP, Saez E, Bleich M, Himmerkus N, Weisz OA, Cravatt BF, Krüger M, Benton HP, Siuzdak G, Staruschenko A. Rinschen MM, et al. Among authors: dissanayake lv. Nat Commun. 2022 Jul 14;13(1):4099. doi: 10.1038/s41467-022-31670-0. Nat Commun. 2022. PMID: 35835746 Free PMC article.
Characterization of purinergic receptor expression in ARPKD cystic epithelia.
Palygin O, Ilatovskaya DV, Levchenko V, Klemens CA, Dissanayake L, Williams AM, Pavlov TS, Staruschenko A. Palygin O, et al. Purinergic Signal. 2018 Dec;14(4):485-497. doi: 10.1007/s11302-018-9632-5. Epub 2018 Nov 11. Purinergic Signal. 2018. PMID: 30417216 Free PMC article.
Effects of uric acid dysregulation on the kidney.
Dissanayake LV, Spires DR, Palygin O, Staruschenko A. Dissanayake LV, et al. Am J Physiol Renal Physiol. 2020 May 1;318(5):F1252-F1257. doi: 10.1152/ajprenal.00066.2020. Epub 2020 Mar 30. Am J Physiol Renal Physiol. 2020. PMID: 32223309 Free PMC article.
Knockout of the Circadian Clock Protein PER1 (Period1) Exacerbates Hypertension and Increases Kidney Injury in Dahl Salt-Sensitive Rats.
Zietara A, Spires DR, Juffre A, Costello HM, Crislip GR, Douma LG, Levchenko V, Dissanayake LV, Klemens CA, Nikolaienko O, Geurts AM, Gumz ML, Staruschenko A. Zietara A, et al. Among authors: dissanayake lv. Hypertension. 2022 Nov;79(11):2519-2529. doi: 10.1161/HYPERTENSIONAHA.122.19316. Epub 2022 Sep 12. Hypertension. 2022. PMID: 36093781 Free PMC article.
Kir7.1 knockdown and inhibition alter renal electrolyte handling but not the development of hypertension in Dahl salt-sensitive rats.
Zietara A, Palygin O, Levchenko V, Dissanayake LV, Klemens CA, Geurts A, Denton JS, Staruschenko A. Zietara A, et al. Among authors: dissanayake lv. Am J Physiol Renal Physiol. 2023 Aug 1;325(2):F177-F187. doi: 10.1152/ajprenal.00059.2023. Epub 2023 Jun 15. Am J Physiol Renal Physiol. 2023. PMID: 37318990 Free PMC article.
Lysine and salt-sensitive hypertension.
Dissanayake LV, Palygin O, Staruschenko A. Dissanayake LV, et al. Curr Opin Nephrol Hypertens. 2024 Jul 1;33(4):441-446. doi: 10.1097/MNH.0000000000000994. Epub 2024 Apr 19. Curr Opin Nephrol Hypertens. 2024. PMID: 38639736 Review.
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