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Page 1
Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis.
Borie R, Cardwell J, Konigsberg IR, Moore CM, Zhang W, Sasse SK, Gally F, Dobrinskikh E, Walts A, Powers J, Brancato J, Rojas M, Wolters PJ, Brown KK, Blackwell TS, Nakanishi T, Richards JB, Gerber AN, Fingerlin TE, Sachs N, Pulit SL, Zappala Z, Schwartz DA, Yang IV. Borie R, et al. Among authors: dobrinskikh e. Am J Respir Crit Care Med. 2022 Nov 15;206(10):1259-1270. doi: 10.1164/rccm.202110-2308OC. Am J Respir Crit Care Med. 2022. PMID: 35816432 Free PMC article.
MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease.
Juge PA, Lee JS, Ebstein E, Furukawa H, Dobrinskikh E, Gazal S, Kannengiesser C, Ottaviani S, Oka S, Tohma S, Tsuchiya N, Rojas-Serrano J, González-Pérez MI, Mejía M, Buendía-Roldán I, Falfán-Valencia R, Ambrocio-Ortiz E, Manali E, Papiris SA, Karageorgas T, Boumpas D, Antoniou K, van Moorsel CHM, van der Vis J, de Man YA, Grutters JC, Wang Y, Borie R, Wemeau-Stervinou L, Wallaert B, Flipo RM, Nunes H, Valeyre D, Saidenberg-Kermanac'h N, Boissier MC, Marchand-Adam S, Frazier A, Richette P, Allanore Y, Sibilia J, Dromer C, Richez C, Schaeverbeke T, Lioté H, Thabut G, Nathan N, Amselem S, Soubrier M, Cottin V, Clément A, Deane K, Walts AD, Fingerlin T, Fischer A, Ryu JH, Matteson EL, Niewold TB, Assayag D, Gross A, Wolters P, Schwarz MI, Holers M, Solomon JJ, Doyle T, Rosas IO, Blauwendraat C, Nalls MA, Debray MP, Boileau C, Crestani B, Schwartz DA, Dieudé P. Juge PA, et al. Among authors: dobrinskikh e. N Engl J Med. 2018 Dec 6;379(23):2209-2219. doi: 10.1056/NEJMoa1801562. Epub 2018 Oct 20. N Engl J Med. 2018. PMID: 30345907 Free PMC article.
Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice.
Hancock LA, Hennessy CE, Solomon GM, Dobrinskikh E, Estrella A, Hara N, Hill DB, Kissner WJ, Markovetz MR, Grove Villalon DE, Voss ME, Tearney GJ, Carroll KS, Shi Y, Schwarz MI, Thelin WR, Rowe SM, Yang IV, Evans CM, Schwartz DA. Hancock LA, et al. Among authors: dobrinskikh e. Nat Commun. 2018 Dec 18;9(1):5363. doi: 10.1038/s41467-018-07768-9. Nat Commun. 2018. PMID: 30560893 Free PMC article.
Muc5b Enhances Murine Honeycomb-like Cyst Formation.
Kurche JS, Dobrinskikh E, Hennessy CE, Huber J, Estrella A, Hancock LA, Schwarz MI, Okamoto T, Cool CD, Yang IV, Evans CM, Schwartz DA. Kurche JS, et al. Among authors: dobrinskikh e. Am J Respir Cell Mol Biol. 2019 Oct;61(4):544-546. doi: 10.1165/rcmb.2019-0138LE. Am J Respir Cell Mol Biol. 2019. PMID: 31573335 Free PMC article. No abstract available.
Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis.
Lee JS, La J, Aziz S, Dobrinskikh E, Brownell R, Jones KD, Achtar-Zadeh N, Green G, Elicker BM, Golden JA, Matthay MA, Kukreja J, Schwartz DA, Wolters PJ. Lee JS, et al. Among authors: dobrinskikh e. Histopathology. 2021 Jul;79(1):67-76. doi: 10.1111/his.14334. Epub 2021 Apr 14. Histopathology. 2021. PMID: 33432658 Free PMC article.
Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis.
Dobrinskikh E, Estrella AM, Hennessy CE, Hara N, Schwarz MI, Kurche JS, Yang IV, Schwartz DA. Dobrinskikh E, et al. Am J Physiol Lung Cell Mol Physiol. 2021 Aug 1;321(2):L440-L450. doi: 10.1152/ajplung.00615.2020. Epub 2021 Jun 23. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34160296 Free PMC article.
Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis.
Heinzelmann K, Hu Q, Hu Y, Dobrinskikh E, Ansari M, Melo-Narváez MC, Ulke HM, Leavitt C, Mirita C, Trudeau T, Saal ML, Rice P, Gao B, Janssen WJ, Yang IV, Schiller HB, Vladar EK, Lehmann M, Königshoff M. Heinzelmann K, et al. Among authors: dobrinskikh e. Eur Respir J. 2022 Jun 16;59(6):2102373. doi: 10.1183/13993003.02373-2021. Print 2022 Jun. Eur Respir J. 2022. PMID: 35604813 Free PMC article.
Aberrant Multiciliogenesis in Idiopathic Pulmonary Fibrosis.
Kim E, Mathai SK, Stancil IT, Ma X, Hernandez-Gutierrez A, Becerra JN, Marrero-Torres E, Hennessy CE, Hatakka K, Wartchow EP, Estrella A, Huber JP, Cardwell JH, Burnham EL, Zhang Y, Evans CM, Vladar EK, Schwartz DA, Dobrinskikh E, Yang IV. Kim E, et al. Among authors: dobrinskikh e. Am J Respir Cell Mol Biol. 2022 Aug;67(2):188-200. doi: 10.1165/rcmb.2021-0554OC. Am J Respir Cell Mol Biol. 2022. PMID: 35608953 Free PMC article.
64 results