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Upper airway gene expression shows a more robust adaptive immune response to SARS-CoV-2 in children.
Mick E, Tsitsiklis A, Spottiswoode N, Caldera S, Serpa PH, Detweiler AM, Neff N, Pisco AO, Li LM, Retallack H, Ratnasiri K, Williamson KM, Soesanto V, Simões EAF, Smith C, Abuogi L, Kistler A, Wagner BD, DeRisi JL, Ambroggio L, Mourani PM, Langelier CR. Mick E, et al. Among authors: langelier cr. Nat Commun. 2022 Jul 8;13(1):3937. doi: 10.1038/s41467-022-31600-0. Nat Commun. 2022. PMID: 35803954 Free PMC article.
Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants.
Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Network I, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf J, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar W, Maecker H, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Augustine AD, Sekaly RP, Ehrlich LIR, Fourati S, Peters B, Kleinstein SH, Guan L. Gygi JP, et al. Among authors: langelier cr. bioRxiv [Preprint]. 2023 Nov 6:2023.11.03.565292. doi: 10.1101/2023.11.03.565292. bioRxiv. 2023. Update in: J Clin Invest. 2024 May 1;134(9):e176640. doi: 10.1172/JCI176640 PMID: 37986828 Free PMC article. Updated. Preprint.
Doxycycline post-exposure prophylaxis for sexually transmitted infections impacts the gut antimicrobial resistome.
Langelier C, Chu V, Glascock A, Donnell D, Grabow C, Brown C, Ward R, Love C, Kalantar K, Cohen S, Cannon C, Woodworth M, Kelley C, Celum C, Luetkemeyer A. Langelier C, et al. Res Sq [Preprint]. 2024 Apr 17:rs.3.rs-4243341. doi: 10.21203/rs.3.rs-4243341/v1. Res Sq. 2024. Update in: Nat Med. 2024 Oct 3. doi: 10.1038/s41591-024-03274-2 PMID: 38699315 Free PMC article. Updated. Preprint.
IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma.
Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG. Bhakta NR, et al. Am J Respir Crit Care Med. 2018 Feb 1;197(3):313-324. doi: 10.1164/rccm.201706-1070OC. Am J Respir Crit Care Med. 2018. PMID: 29064281 Free PMC article.
Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children.
Zinter MS, Dvorak CC, Mayday MY, Iwanaga K, Ly NP, McGarry ME, Church GD, Faricy LE, Rowan CM, Hume JR, Steiner ME, Crawford ED, Langelier C, Kalantar K, Chow ED, Miller S, Shimano K, Melton A, Yanik GA, Sapru A, DeRisi JL. Zinter MS, et al. Clin Infect Dis. 2019 May 17;68(11):1847-1855. doi: 10.1093/cid/ciy802. Clin Infect Dis. 2019. PMID: 30239621 Free PMC article.
Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.
Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. Langelier C, et al. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12353-E12362. doi: 10.1073/pnas.1809700115. Epub 2018 Nov 27. Proc Natl Acad Sci U S A. 2018. PMID: 30482864 Free PMC article.
Metagenomic comparison of tracheal aspirate and mini-bronchial alveolar lavage for assessment of respiratory microbiota.
Kalantar KL, Moazed F, Christenson SC, Wilson J, Deiss T, Belzer A, Vessel K, Caldera S, Jauregui A, Bolourchi S, DeRisi JL, Calfee CS, Langelier C. Kalantar KL, et al. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L578-L584. doi: 10.1152/ajplung.00476.2018. Epub 2019 Jan 17. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30652494 Free PMC article.
141 results