Chen CH - Search Results

1

Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1.

Feng Z, Hom ME, Bearrood TE, Rosenthal ZC, Fernández D, Ondrus AE, Gu Y, McCormick AK, Tomaske MG, Marshall CR, Kline T, Chen CH, Mochly-Rosen D, Kuo CJ, Chen JK. Feng Z, et al. Among authors: chen jk, chen ch. Nat Chem Biol. 2022 Oct;18(10):1065-1075. doi: 10.1038/s41589-022-01048-w. Epub 2022 Jul 4. Nat Chem Biol. 2022. PMID: 35788181 Free PMC article.

2

A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function.

Johnson JA, Gray MO, Chen CH, Mochly-Rosen D. Johnson JA, et al. Among authors: chen ch. J Biol Chem. 1996 Oct 4;271(40):24962-6. doi: 10.1074/jbc.271.40.24962. J Biol Chem. 1996. PMID: 8798776 Free article.

3

An improved permeabilization protocol for the introduction of peptides into cardiac myocytes. Application to protein kinase C research.

Johnson JA, Gray MO, Karliner JS, Chen CH, Mochly-Rosen D. Johnson JA, et al. Among authors: chen ch. Circ Res. 1996 Dec;79(6):1086-99. doi: 10.1161/01.res.79.6.1086. Circ Res. 1996. PMID: 8943947

4

Characterization of the binding and phosphorylation of cardiac calsequestrin by epsilon protein kinase C.

Rodriguez MM, Chen CH, Smith BL, Mochly-Rosen D. Rodriguez MM, et al. Among authors: chen ch. FEBS Lett. 1999 Jul 9;454(3):240-6. doi: 10.1016/s0014-5793(99)00697-3. FEBS Lett. 1999. PMID: 10431815 Free article.

5

Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: role of epsilon protein kinase C.

Chen CH, Gray MO, Mochly-Rosen D. Chen CH, et al. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12784-9. doi: 10.1073/pnas.96.22.12784. Proc Natl Acad Sci U S A. 1999. PMID: 10536000 Free PMC article.

6

Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7).

Chen L, Wright LR, Chen CH, Oliver SF, Wender PA, Mochly-Rosen D. Chen L, et al. Among authors: chen ch. Chem Biol. 2001 Dec;8(12):1123-9. doi: 10.1016/s1074-5521(01)00076-x. Chem Biol. 2001. PMID: 11755391

7

Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart.

Chen CH, Budas GR, Churchill EN, Disatnik MH, Hurley TD, Mochly-Rosen D. Chen CH, et al. Science. 2008 Sep 12;321(5895):1493-5. doi: 10.1126/science.1158554. Science. 2008. PMID: 18787169 Free PMC article.

8

Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice.

Budas GR, Disatnik MH, Chen CH, Mochly-Rosen D. Budas GR, et al. Among authors: chen ch. J Mol Cell Cardiol. 2010 Apr;48(4):757-64. doi: 10.1016/j.yjmcc.2009.10.030. Epub 2009 Nov 11. J Mol Cell Cardiol. 2010. PMID: 19913552 Free PMC article.

9

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant.

Perez-Miller S, Younus H, Vanam R, Chen CH, Mochly-Rosen D, Hurley TD. Perez-Miller S, et al. Among authors: chen ch. Nat Struct Mol Biol. 2010 Feb;17(2):159-64. doi: 10.1038/nsmb.1737. Epub 2010 Jan 10. Nat Struct Mol Biol. 2010. PMID: 20062057 Free PMC article.

10

Mitochondrial aldehyde dehydrogenase and cardiac diseases.

Chen CH, Sun L, Mochly-Rosen D. Chen CH, et al. Cardiovasc Res. 2010 Oct 1;88(1):51-7. doi: 10.1093/cvr/cvq192. Epub 2010 Jun 16. Cardiovasc Res. 2010. PMID: 20558439 Free PMC article. Review.

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