Gamal El-Din TM - Search Results

1

Editorial: Structure Related Druggability of Voltage-Gated Sodium and Calcium Ion-Channels to Treat Diseases.

Gamal El-Din TM, Zimmer T, Chahine M. Gamal El-Din TM, et al. Front Pharmacol. 2022 Jun 15;13:947511. doi: 10.3389/fphar.2022.947511. eCollection 2022. Front Pharmacol. 2022. PMID: 35784759 Free PMC article. No abstract available.

2

Novel G1481V and Q1491H SCN5A Mutations Linked to Long QT Syndrome Destabilize the Nav1.5 Inactivation State.

Plumereau Q, Theriault O, Pouliot V, Moreau A, Morel E, Fressart V, Denjoy I, Delinière A, Bessière F, Chevalier P, Gamal El-Din TM, Chahine M. Plumereau Q, et al. CJC Open. 2020 Oct 5;3(3):256-266. doi: 10.1016/j.cjco.2020.09.023. eCollection 2021 Mar. CJC Open. 2020. PMID: 33778442 Free PMC article.

3

Fenestropathy of Voltage-Gated Sodium Channels.

Gamal El-Din TM, Lenaeus MJ. Gamal El-Din TM, et al. Front Pharmacol. 2022 Feb 11;13:842645. doi: 10.3389/fphar.2022.842645. eCollection 2022. Front Pharmacol. 2022. PMID: 35222049 Free PMC article. Review.

4

Druggability of Voltage-Gated Sodium Channels-Exploring Old and New Drug Receptor Sites.

Wisedchaisri G, Gamal El-Din TM. Wisedchaisri G, et al. Front Pharmacol. 2022 Mar 17;13:858348. doi: 10.3389/fphar.2022.858348. eCollection 2022. Front Pharmacol. 2022. PMID: 35370700 Free PMC article. Review.

5

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.

Payandeh J, Gamal El-Din TM, Scheuer T, Zheng N, Catterall WA. Payandeh J, et al. Nature. 2012 May 20;486(7401):135-9. doi: 10.1038/nature11077. Nature. 2012. PMID: 22678296 Free PMC article.

6

Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective.

Gamal El-Din TM, Lenaeus MJ, Catterall WA. Gamal El-Din TM, et al. Handb Exp Pharmacol. 2018;246:53-72. doi: 10.1007/164_2017_61. Handb Exp Pharmacol. 2018. PMID: 29043505 Review.

7

Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels.

Catterall WA, Lenaeus MJ, Gamal El-Din TM. Catterall WA, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:133-154. doi: 10.1146/annurev-pharmtox-010818-021757. Epub 2019 Sep 19. Annu Rev Pharmacol Toxicol. 2020. PMID: 31537174 Review.

8

Structural Basis for Diltiazem Block of a Voltage-Gated Ca²⁺ Channel.

Tang L, Gamal El-Din TM, Lenaeus MJ, Zheng N, Catterall WA. Tang L, et al. Mol Pharmacol. 2019 Oct;96(4):485-492. doi: 10.1124/mol.119.117531. Epub 2019 Aug 7. Mol Pharmacol. 2019. PMID: 31391290 Free PMC article.

9

Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na_V1.7.

Wisedchaisri G, Gamal El-Din TM, Zheng N, Catterall WA. Wisedchaisri G, et al. Among authors: gamal el din tm. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2219624120. doi: 10.1073/pnas.2219624120. Epub 2023 Mar 30. Proc Natl Acad Sci U S A. 2023. PMID: 36996107 Free PMC article.

10

Structures of closed and open states of a voltage-gated sodium channel.

Lenaeus MJ, Gamal El-Din TM, Ing C, Ramanadane K, Pomès R, Zheng N, Catterall WA. Lenaeus MJ, et al. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):E3051-E3060. doi: 10.1073/pnas.1700761114. Epub 2017 Mar 27. Proc Natl Acad Sci U S A. 2017. PMID: 28348242 Free PMC article.

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