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Page 1
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.
Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho BK, Gutierrez Diaz BT, Calvo J, Fang C, Khodadadi-Jamayran A, Tabaglio T, Marier C, Kuchmiy A, Sun L, Yacu G, Filip SK, Jin Q, Takahashi YH, Amici DR, Rendleman EJ, Rawat R, Bresolin S, Paganin M, Zhang C, Li H, Kandela I, Politanska Y, Abdala-Valencia H, Mendillo ML, Zhu P, Palhais B, Van Vlierberghe P, Taghon T, Aifantis I, Goo YA, Guccione E, Heguy A, Tsirigos A, Wee KB, Mishra RK, Pflumio F, Accordi B, Basso G, Ntziachristos P. Zhou Y, et al. Among authors: amici dr. Cancer Discov. 2020 Sep;10(9):1388-1409. doi: 10.1158/2159-8290.CD-19-1436. Epub 2020 May 22. Cancer Discov. 2020. PMID: 32444465 Free PMC article.
HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state.
Smith RS, Takagishi SR, Amici DR, Metz K, Gayatri S, Alasady MJ, Wu Y, Brockway S, Taiberg SL, Khalatyan N, Taipale M, Santagata S, Whitesell L, Lindquist S, Savas JN, Mendillo ML. Smith RS, et al. Among authors: amici dr. Sci Adv. 2022 Mar 18;8(11):eabj6526. doi: 10.1126/sciadv.abj6526. Epub 2022 Mar 16. Sci Adv. 2022. PMID: 35294249 Free PMC article.
C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.
Amici DR, Ansel DJ, Metz KA, Smith RS, Phoumyvong CM, Gayatri S, Chamera T, Edwards SL, O'Hara BP, Srivastava S, Brockway S, Takagishi SR, Cho BK, Goo YA, Kelleher NL, Ben-Sahra I, Foltz DR, Li J, Mendillo ML. Amici DR, et al. Proc Natl Acad Sci U S A. 2022 Jul 5;119(27):e2111262119. doi: 10.1073/pnas.2111262119. Epub 2022 Jul 1. Proc Natl Acad Sci U S A. 2022. PMID: 35776542 Free PMC article.
Tight regulation of a nuclear HAPSTR1-HUWE1 pathway essential for mammalian life.
Amici DR, Alhayek S, Klein AT, Wang YZ, Wilen AP, Song W, Zhu P, Thakkar A, King MA, Steffeck AW, Alasady MJ, Peek C, Savas JN, Mendillo ML. Amici DR, et al. Life Sci Alliance. 2024 Mar 7;7(5):e202302370. doi: 10.26508/lsa.202302370. Print 2024 May. Life Sci Alliance. 2024. PMID: 38453366 Free PMC article.
An HSF1-JMJD6-HSP feedback circuit promotes cell adaptation to proteotoxic stress.
Alasady MJ, Koeva M, Takagishi SR, Segal D, Amici DR, Smith RS, Ansel DJ, Lindquist S, Whitesell L, Bartom ET, Taipale M, Mendillo ML. Alasady MJ, et al. Among authors: amici dr. Proc Natl Acad Sci U S A. 2024 Jul 16;121(29):e2313370121. doi: 10.1073/pnas.2313370121. Epub 2024 Jul 10. Proc Natl Acad Sci U S A. 2024. PMID: 38985769
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