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Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate.
Freire MCLC, Basso LGM, Mendes LFS, Mesquita NCMR, Mottin M, Fernandes RS, Policastro LR, Godoy AS, Santos IA, Ruiz UEA, Caruso IP, Sousa BKP, Jardim ACG, Almeida FCL, Gil LHVG, Andrade CH, Oliva G. Freire MCLC, et al. Among authors: fernandes rs. Sci Rep. 2022 Jun 22;12(1):10601. doi: 10.1038/s41598-022-14790-x. Sci Rep. 2022. PMID: 35732685 Free PMC article.
A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process.
Noske GD, Nakamura AM, Gawriljuk VO, Fernandes RS, Lima GMA, Rosa HVD, Pereira HD, Zeri ACM, Nascimento AFZ, Freire MCLC, Fearon D, Douangamath A, von Delft F, Oliva G, Godoy AS. Noske GD, et al. Among authors: fernandes rs. J Mol Biol. 2021 Sep 3;433(18):167118. doi: 10.1016/j.jmb.2021.167118. Epub 2021 Jun 24. J Mol Biol. 2021. PMID: 34174328 Free PMC article. Review.
Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors.
Freire MCLC, Noske GD, Bitencourt NV, Sanches PRS, Santos-Filho NA, Gawriljuk VO, de Souza EP, Nogueira VHR, de Godoy MO, Nakamura AM, Fernandes RS, Godoy AS, Juliano MA, Peres BM, Barbosa CG, Moraes CB, Freitas-Junior LHG, Cilli EM, Guido RVC, Oliva G. Freire MCLC, et al. Among authors: fernandes rs. Molecules. 2021 Aug 12;26(16):4896. doi: 10.3390/molecules26164896. Molecules. 2021. PMID: 34443484 Free PMC article.
Pyronaridine Protects against SARS-CoV-2 Infection in Mouse.
Puhl AC, Gomes GF, Damasceno S, Godoy AS, Noske GD, Nakamura AM, Gawriljuk VO, Fernandes RS, Monakhova N, Riabova O, Lane TR, Makarov V, Veras FP, Batah SS, Fabro AT, Oliva G, Cunha FQ, Alves-Filho JC, Cunha TM, Ekins S. Puhl AC, et al. Among authors: fernandes rs. ACS Infect Dis. 2022 Jun 10;8(6):1147-1160. doi: 10.1021/acsinfecdis.2c00091. Epub 2022 May 24. ACS Infect Dis. 2022. PMID: 35609344
The Antifungal Itraconazole Is a Potent Inhibitor of Chikungunya Virus Replication.
Policastro LR, Dolci I, Godoy AS, Silva Júnior JVJ, Ruiz UEA, Santos IA, Jardim ACG, Samby K, Burrows JN, Wells TNC, Gil LHVG, Oliva G, Fernandes RS. Policastro LR, et al. Among authors: fernandes rs. Viruses. 2022 Jun 21;14(7):1351. doi: 10.3390/v14071351. Viruses. 2022. PMID: 35891332 Free PMC article.
Imidazonaphthyridine effects on Chikungunya virus replication: Antiviral activity by dependent and independent of interferon type 1 pathways.
Ruiz UEA, Santos IA, Grosche VR, Fernandes RS, de Godoy AS, Torres JDA, Freire MCLC, Mesquita NCMR, Guevara-Vega M, Nicolau-Junior N, Sabino-Silva R, Mineo TWP, Oliva G, Jardim ACG. Ruiz UEA, et al. Among authors: fernandes rs. Virus Res. 2023 Jan 15;324:199029. doi: 10.1016/j.virusres.2022.199029. Epub 2022 Dec 22. Virus Res. 2023. PMID: 36565816 Free PMC article.
119 results