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Tubular CPT1A deletion minimally affects aging and chronic kidney injury.
Hammoud S, Ivanova A, Osaki Y, Funk S, Yang H, Viquez O, Delgado R, Lu D, Phillips Mignemi M, Tonello J, Colon S, Lantier L, Wasserman DH, Humphreys BD, Koenitzer J, Kern J, de Caestecker M, Finkel T, Fogo A, Messias N, Lodhi IJ, Gewin LS. Hammoud S, et al. Among authors: kern j. JCI Insight. 2024 Feb 22;9(6):e171961. doi: 10.1172/jci.insight.171961. JCI Insight. 2024. PMID: 38516886 Free PMC article.
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction.
Sun S, Hodel M, Wang X, De Vicente J, Haritunians T, Debebe A, Hung CT, Ma C, Malique A, Nguyen HN, Agam M, Maloney MT, Goo MS, Kluss JH, Mishra R, Frein J, Foster A, Ballentine S, Pandey U, Kern J, Yang S, Mengesha E, Balasubramanian I, Arguello A, Estrada AA, Gao N, Peter I, McGovern DPB, Henry AG, Stappenbeck TS, Liu TC. Sun S, et al. Among authors: kern j. Sci Immunol. 2024 Nov 8;9(101):eadi7907. doi: 10.1126/sciimmunol.adi7907. Epub 2024 Nov 8. Sci Immunol. 2024. PMID: 39514635
Debaryomyces is enriched in Crohn's disease intestinal tissue and impairs healing in mice.
Jain U, Ver Heul AM, Xiong S, Gregory MH, Demers EG, Kern JT, Lai CW, Muegge BD, Barisas DAG, Leal-Ekman JS, Deepak P, Ciorba MA, Liu TC, Hogan DA, Debbas P, Braun J, McGovern DPB, Underhill DM, Stappenbeck TS. Jain U, et al. Among authors: kern jt. Science. 2021 Mar 12;371(6534):1154-1159. doi: 10.1126/science.abd0919. Science. 2021. PMID: 33707263 Free PMC article.
Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation.
Liu TC, Kern JT, Jain U, Sonnek NM, Xiong S, Simpson KF, VanDussen KL, Winkler ES, Haritunians T, Malique A, Lu Q, Sasaki Y, Storer C, Diamond MS, Head RD, McGovern DPB, Stappenbeck TS. Liu TC, et al. Cell Host Microbe. 2021 Jun 9;29(6):988-1001.e6. doi: 10.1016/j.chom.2021.04.004. Epub 2021 May 18. Cell Host Microbe. 2021. PMID: 34010595 Free PMC article.
Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients.
Dousset L, Chambers DC, Webster A, Isbel N, Campbell S, Duarte C, Collins L, Damian D, Tseng A, Karlsen E, Ilinsky OV, Brown S, Schaider H, Soyer HP, Ospino DA, Hogarth S, Chong AH, Mar V, McKenzie S, Gin D, Fernandez-Penas P, Kern JS, Loewe K, Roy E, Herschtal A, Khosrotehrani K. Dousset L, et al. Among authors: kern js. Trials. 2024 Nov 22;25(1):789. doi: 10.1186/s13063-024-08619-3. Trials. 2024. PMID: 39578921
1,474 results