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DXS as a target for structure-based drug design.
Gierse RM, Redeem E, Diamanti E, Wrenger C, Groves MR, Hirsch AK. Gierse RM, et al. Among authors: diamanti e. Future Med Chem. 2017 Jul;9(11):1277-1294. doi: 10.4155/fmc-2016-0239. Epub 2017 Jun 21. Future Med Chem. 2017. PMID: 28636418 Review.
Assessment of the rules related to gaining activity against Gram-negative bacteria.
Ropponen HK, Diamanti E, Siemens A, Illarionov B, Haupenthal J, Fischer M, Rottmann M, Witschel M, Hirsch AKH. Ropponen HK, et al. Among authors: diamanti e. RSC Med Chem. 2021 Mar 3;12(4):593-601. doi: 10.1039/d0md00409j. eCollection 2021 Apr 28. RSC Med Chem. 2021. PMID: 34046630 Free PMC article.
Targeting Plasmodium falciparum IspD in the Methyl-d-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity.
Willocx D, Bizzarri L, Alhayek A, Kannan D, Bravo P, Illarionov B, Rox K, Lohse J, Fischer M, Kany AM, Hahne H, Rottmann M, Witschel M, Odom John A, Hamed MM, Diamanti E, Hirsch AKH. Willocx D, et al. Among authors: diamanti e. J Med Chem. 2024 Oct 10;67(19):17070-17086. doi: 10.1021/acs.jmedchem.4c00212. Epub 2024 Sep 20. J Med Chem. 2024. PMID: 39303294 Free PMC article.
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement.
Mammoli V, Bonifazi A, Del Bello F, Diamanti E, Giannella M, Hudson AL, Mattioli L, Perfumi M, Piergentili A, Quaglia W, Titomanlio F, Pigini M. Mammoli V, et al. Among authors: diamanti e. Bioorg Med Chem. 2012 Apr 1;20(7):2259-65. doi: 10.1016/j.bmc.2012.02.016. Epub 2012 Feb 13. Bioorg Med Chem. 2012. PMID: 22370341
170 results