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Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine.
Gigoux M, Holmström MO, Zappasodi R, Park JJ, Pourpe S, Bozkus CC, Mangarin LMB, Redmond D, Verma S, Schad S, George MM, Venkatesh D, Ghosh A, Hoyos D, Molvi Z, Kamaz B, Marneth AE, Duke W, Leventhal MJ, Jan M, Ho VT, Hobbs GS, Knudsen TA, Skov V, Kjær L, Larsen TS, Hansen DL, Lindsley RC, Hasselbalch H, Grauslund JH, Lisle TL, Met Ö, Wilkinson P, Greenbaum B, Sepulveda MA, Chan T, Rampal R, Andersen MH, Abdel-Wahab O, Bhardwaj N, Wolchok JD, Mullally A, Merghoub T. Gigoux M, et al. Among authors: molvi z. Sci Transl Med. 2022 Jun 15;14(649):eaba4380. doi: 10.1126/scitranslmed.aba4380. Epub 2022 Jun 15. Sci Transl Med. 2022. PMID: 35704596 Free PMC article.
Challenges and solutions for therapeutic TCR-based agents.
Malviya M, Aretz ZEH, Molvi Z, Lee J, Pierre S, Wallisch P, Dao T, Scheinberg DA. Malviya M, et al. Among authors: molvi z. Immunol Rev. 2023 Nov;320(1):58-82. doi: 10.1111/imr.13233. Epub 2023 Jul 16. Immunol Rev. 2023. PMID: 37455333 Review.
Magnetic susceptibility increases as diamagnetic molecules breakdown: Myelin digestion during multiple sclerosis lesion formation contributes to increase on QSM.
Deh K, Ponath GD, Molvi Z, Parel GT, Gillen KM, Zhang S, Nguyen TD, Spincemaille P, Ma Y, Gupta A, Gauthier SA, Pitt D, Wang Y. Deh K, et al. Among authors: molvi z. J Magn Reson Imaging. 2018 Nov;48(5):1281-1287. doi: 10.1002/jmri.25997. Epub 2018 Mar 8. J Magn Reson Imaging. 2018. PMID: 29517817 Free PMC article.
89Zr-immunoPET-guided selection of a CD33xIL15 fusion protein optimized for antitumor immune cell activation and in vivo tumour retention in acute myeloid leukaemia.
Herrero Alvarez N, Molvi Z, Lupo K, Urraca J, Balderes P, Nyakatura EK, Khan AG, Viray T, Lewis JS, O'Reilly RJ. Herrero Alvarez N, et al. Among authors: molvi z. Eur J Nucl Med Mol Imaging. 2024 Jul 11. doi: 10.1007/s00259-024-06814-7. Online ahead of print. Eur J Nucl Med Mol Imaging. 2024. PMID: 38987489
12 results