Garcia BL - Search Results

1

Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions.

Booth CE Jr, Powell-Pierce AD, Skare JT, Garcia BL. Booth CE Jr, et al. Among authors: garcia bl. Front Immunol. 2022 May 27;13:886733. doi: 10.3389/fimmu.2022.886733. eCollection 2022. Front Immunol. 2022. PMID: 35693799 Free PMC article.

2

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex.

Garcia BL, Zhi H, Wager B, Höök M, Skare JT. Garcia BL, et al. PLoS Pathog. 2016 Jan 25;12(1):e1005404. doi: 10.1371/journal.ppat.1005404. eCollection 2016 Jan. PLoS Pathog. 2016. PMID: 26808924 Free PMC article.

3

Structural determination of the complement inhibitory domain of Borrelia burgdorferi BBK32 provides insight into classical pathway complement evasion by Lyme disease spirochetes.

Xie J, Zhi H, Garrigues RJ, Keightley A, Garcia BL, Skare JT. Xie J, et al. Among authors: garcia bl. PLoS Pathog. 2019 Mar 21;15(3):e1007659. doi: 10.1371/journal.ppat.1007659. eCollection 2019 Mar. PLoS Pathog. 2019. PMID: 30897158 Free PMC article.

4

Complement Evasion by Lyme Disease Spirochetes.

Skare JT, Garcia BL. Skare JT, et al. Among authors: garcia bl. Trends Microbiol. 2020 Nov;28(11):889-899. doi: 10.1016/j.tim.2020.05.004. Epub 2020 May 29. Trends Microbiol. 2020. PMID: 32482556 Free PMC article. Review.

5

Lyme Disease Pathogenesis.

Coburn J, Garcia B, Hu LT, Jewett MW, Kraiczy P, Norris SJ, Skare J. Coburn J, et al. Curr Issues Mol Biol. 2021;42:473-518. doi: 10.21775/cimb.042.473. Epub 2020 Dec 23. Curr Issues Mol Biol. 2021. PMID: 33353871 Free PMC article. Review.

6

A Structural Basis for Inhibition of the Complement Initiator Protease C1r by Lyme Disease Spirochetes.

Garrigues RJ, Powell-Pierce AD, Hammel M, Skare JT, Garcia BL. Garrigues RJ, et al. Among authors: garcia bl. J Immunol. 2021 Dec 1;207(11):2856-2867. doi: 10.4049/jimmunol.2100815. Epub 2021 Nov 10. J Immunol. 2021. PMID: 34759015 Free PMC article.

7

Lipoproteome screening of the Lyme disease agent identifies inhibitors of antibody-mediated complement killing.

Pereira MJ, Wager B, Garrigues RJ, Gerlach E, Quinn JD, Dowdell AS, Osburne MS, Zückert WR, Kraiczy P, Garcia BL, Leong JM. Pereira MJ, et al. Among authors: garcia bl. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2117770119. doi: 10.1073/pnas.2117770119. Epub 2022 Mar 21. Proc Natl Acad Sci U S A. 2022. PMID: 35312359 Free PMC article.

8

Minimal role for the alternative pathway in complement activation by HIT immune complexes.

Barnes AP, Khandelwal S, Sartoretto S, Myoung S, Francis SJ, Lee GM, Rauova L, Cines DB, Skare JT, Booth CE Jr, Garcia BL, Arepally GM. Barnes AP, et al. Among authors: garcia bl. J Thromb Haemost. 2022 Nov;20(11):2656-2665. doi: 10.1111/jth.15856. Epub 2022 Sep 1. J Thromb Haemost. 2022. PMID: 35996342 Free PMC article.

9

Outer surface lipoproteins from the Lyme disease spirochete exploit the molecular switch mechanism of the complement protease C1s.

Garrigues RJ, Thomas S, Leong JM, Garcia BL. Garrigues RJ, et al. Among authors: garcia bl. J Biol Chem. 2022 Nov;298(11):102557. doi: 10.1016/j.jbc.2022.102557. Epub 2022 Sep 29. J Biol Chem. 2022. PMID: 36183830 Free PMC article.

10

Targeting the Initiator Protease of the Classical Pathway of Complement Using Fragment-Based Drug Discovery.

Rushing BR, Rohlik DL, Roy S, Skaff DA, Garcia BL. Rushing BR, et al. Among authors: garcia bl. Molecules. 2020 Sep 3;25(17):4016. doi: 10.3390/molecules25174016. Molecules. 2020. PMID: 32899120 Free PMC article.

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