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Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment.
Wang L, Liu Y, Dai Y, Tang X, Yin T, Wang C, Wang T, Dong L, Shi M, Qin J, Xue M, Cao Y, Liu J, Liu P, Huang J, Wen C, Zhang J, Xu Z, Bai F, Deng X, Peng C, Chen H, Jiang L, Chen S, Shen B. Wang L, et al. Among authors: wang t, wang c. Gut. 2023 May;72(5):958-971. doi: 10.1136/gutjnl-2021-326070. Epub 2022 Jun 10. Gut. 2023. PMID: 35688610 Free PMC article.
An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma.
Wen CL, Huang K, Jiang LL, Lu XX, Dai YT, Shi MM, Tang XM, Wang QB, Zhang XD, Wang PH, Li HT, Ruan XX, Wang LW, Wang XJ, Wang Q, Lu W, Xiang XQ, Sun X, Xu YH, Lai LH, Zhan Q, Li HW, Peng CH, Chen J, Huang JY, Ye DY, Chen SJ, Chen Z, Li M, Fang Y, Shen BY, Zhou L. Wen CL, et al. Among authors: wang lw, wang xj, wang qb, wang ph, wang q. Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23264-23273. doi: 10.1073/pnas.1914557116. Epub 2019 Oct 29. Proc Natl Acad Sci U S A. 2019. PMID: 31662475 Free PMC article.
Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment.
Xue M, Zhu Y, Jiang Y, Han L, Shi M, Su R, Wang L, Xiong C, Wang C, Wang T, Deng S, Wu D, Cao Y, Dong L, Bai F, Zhao S, Deng X, Peng C, Li H, Chen J, Shen B, Jiang L, Chen H. Xue M, et al. Among authors: wang l, wang t, wang c. Nat Commun. 2023 Jul 31;14(1):4600. doi: 10.1038/s41467-023-40314-w. Nat Commun. 2023. PMID: 37524695 Free PMC article.
BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1.
Cao Y, Wang X, Liu Y, Liu P, Qin J, Zhu Y, Zhai S, Jiang Y, Liu Y, Han L, Luo J, Zhang R, Shi M, Wang L, Tang X, Xue M, Liu J, Wang W, Wen C, Deng X, Peng C, Chen H, Cheng D, Jiang L, Shen B. Cao Y, et al. Among authors: wang x, wang w, wang l. Adv Sci (Weinh). 2024 Feb;11(7):e2306298. doi: 10.1002/advs.202306298. Epub 2023 Dec 8. Adv Sci (Weinh). 2024. PMID: 38064101 Free PMC article.
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