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N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide (TAK-632) Analogues as Novel Necroptosis Inhibitors by Targeting Receptor-Interacting Protein Kinase 3 (RIPK3): Synthesis, Structure-Activity Relationships, and in Vivo Efficacy.
Zhang H, Xu L, Qin X, Chen X, Cong H, Hu L, Chen L, Miao Z, Zhang W, Cai Z, Zhuang C. Zhang H, et al. Among authors: xu l. J Med Chem. 2019 Jul 25;62(14):6665-6681. doi: 10.1021/acs.jmedchem.9b00611. Epub 2019 May 28. J Med Chem. 2019. PMID: 31095385
Targeting Necroptosis as a Promising Therapy for Alzheimer's Disease.
Zhao W, Liu Y, Xu L, He Y, Cai Z, Yu J, Zhang W, Xing C, Zhuang C, Qu Z. Zhao W, et al. Among authors: xu l. ACS Chem Neurosci. 2022 Jun 15;13(12):1697-1713. doi: 10.1021/acschemneuro.2c00172. Epub 2022 May 23. ACS Chem Neurosci. 2022. PMID: 35607807 Review.
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